| Company Name: |
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
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| Tel: |
18818260767 |
| Email: |
sales@chemegen.com |
| Products Intro: |
Product Name:JWH 073 5-hydroxyindole metabolite-d7
CAS:1630022-99-9
Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
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| Company Name: |
Cayman Chemical Company
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| Tel: |
(800) 364-9897 |
| Email: |
cayman@caymanchem.com |
| Products Intro: |
Product Name:JWH 073 5-hydroxyindole metabolite-d7
CAS:1630022-99-9
Package:>=99% deuterated product Remarks:10718
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| | JWH 073 5-hydroxyindole metabolite-d7 Basic information |
| | JWH 073 5-hydroxyindole metabolite-d7 Chemical Properties |
| solubility | DMF: 20 mg/ml; DMSO: 10 mg/ml; Ethanol: 20 mg/ml |
| | JWH 073 5-hydroxyindole metabolite-d7 Usage And Synthesis |
| Description | JWH 073 5-hydroxyindole metabolite-d7 is intended for use as an internal standard for the quantification of JWH 073 5-hydroxyindole metabolite by GC- or LC-MS. JWH 073 is a mildly selective agonist of the central cannabinoid (CB1) receptor derived from the aminoalkylindole WIN 55,212-2. The Ki values for binding CB1 and the peripheral cannabinoid (CB2) receptor are 8.9 and 38 nM, respectively for a CB1:CB2 ratio of 0.23.1 JWH 073 is one of several synthetic CBs which have been included in smoking mixtures. JWH 073 5-hydroxyindole metabolite is expected to be a urinary metabolite of JWH 073 based on the metabolism of the closely-related JWH 015 and JWH 018.2,3 | | References | 1. Aung, M.M., Griffin, G., Huffman, J.W., et al. Influence of the N-1 alkyl chain length of cannabimimetic indoles upon CB1 and CB2 receptor binding Drug Alcohol Depend. 60(2),133-140(2000).
2. Zhang, Q., Ma, P., Cole, R.B., et al. Identification of in vitro metabolites of JWH-015, an aminoalkylindole agonist for the peripheral cannabinoid receptor (CB2) by HPLC-MS/MS Anal. Bioanal. Chem. 386(5),1345-1355(2006).
3. Sobolevsky, T., Prasolov, I., and Rodchenkov, G. Detection of JWH-018 metabolites in smoking mixture post-administration urine Forensic Sci. Int. 200(1-3),141-147(2010). |
| | JWH 073 5-hydroxyindole metabolite-d7 Preparation Products And Raw materials |
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