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| | GNE-495 Basic information |
| Product Name: | GNE-495 | | Synonyms: | GNE-495;8-Amino-N-[1-(cyclopropylcarbonyl)-3-azetidinyl]-2-(3-fluorophenyl)-1,7-naphthyridine-5-carboxamide;8-amino-N-(1-(cyclopropanecarbonyl)azetidin-3-yl)-2-(3-fluorophenyl)-1,7-naphthyridine-5-carboxamide;GNE-495;GNE 495;GNE495;1,7-Naphthyridine-5-carboxamide, 8-amino-N-[1-(cyclopropylcarbonyl)-3-azetidinyl]-2-(3-fluorophenyl)-;MAPK Kinase Kinase Kinase,MAP4K,inhibit,GNE-495,GNE 495,GNE495,Inhibitor | | CAS: | 1449277-10-4 | | MF: | C22H20FN5O2 | | MW: | 405.42 | | EINECS: | | | Product Categories: | | | Mol File: | 1449277-10-4.mol |  |
| | GNE-495 Chemical Properties |
| Boiling point | 734.5±60.0 °C(Predicted) | | density | 1.45±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMSO:3.59(Max Conc. mg/mL);8.85(Max Conc. mM)
DMSO:PBS (pH 7.2) (1:7):0.125(Max Conc. mg/mL);0.31(Max Conc. mM)
DMF:5.0(Max Conc. mg/mL);12.33(Max Conc. mM)
Water:1.0(Max Conc. mg/mL);2.47(Max Conc. mM) | | form | A crystalline solid | | pka | 11.60±0.20(Predicted) |
| | GNE-495 Usage And Synthesis |
| | GNE-495 Preparation Products And Raw materials |
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