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BOC Sciences
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| Products Intro: |
Product Name:PF 06260933 dihydrochloride
CAS:1883548-86-4
Purity:98% by HPLC Remarks:PF 06260933 is a highly selective, orally active and small-molecule inhibitor of MAP4K4 (Mitogen-activated protein kinase kinase kinase kinase 4) (IC50 = 140 nM). It also inhibits MINK and TNIK (IC50=
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| | PF 06260933 dihydrochloride Basic information |
| Product Name: | PF 06260933 dihydrochloride | | Synonyms: | PF 06260933 dihydrochloride;PF 6260933 dihydrochloride;PF-06260933 2HCl;PF-06260933 HCl;PF06260933 HCl,PF 06260933 HCl;PF-06260933 hydrochloride | | CAS: | 1883548-86-4 | | MF: | C16H14Cl2N4 | | MW: | 333.22 | | EINECS: | | | Product Categories: | | | Mol File: | 1883548-86-4.mol |  |
| | PF 06260933 dihydrochloride Chemical Properties |
| solubility | Soluble to 100 mM in water and to 20 mM in DMSO |
| | PF 06260933 dihydrochloride Usage And Synthesis |
| Description | PF-06260933 dihydrochloride is a MAP4K4 (HGK) inhibitor (IC50 = 140 nM). It also inhibits MINK and TNIK (IC50 values are 8 and 13 nM, respectively). PF-06260933 dihydrochloride has been shown to improves fasting hyperglycemia in mice. ( | | storage | Desiccate at RT |
| | PF 06260933 dihydrochloride Preparation Products And Raw materials |
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