PHENMETRAZINE HYDROCHLORIDE CII (200 MG)

PHENMETRAZINE HYDROCHLORIDE CII (200 MG) Basic information
Product Name:PHENMETRAZINE HYDROCHLORIDE CII (200 MG)
Synonyms:3-methyl-2-phenylmorpholinehydrochloride;3-methyl-2-phenyl-morpholinhydrochloride;3-methyl-2-phenyltetrahydro-2h-1,4-oxazinehydrochloride;Preludin;Mefolin;MFCD00242655;Morpholine, 3-methyl-2-phenyl-, hydrochloride;Phenmetrazine hydrochloride (USP)
CAS:1707-14-8
MF:C11H15NO.ClH
MW:213.704
EINECS:216-950-6
Product Categories:Amines;Aromatics;Heterocycles
Mol File:1707-14-8.mol
PHENMETRAZINE HYDROCHLORIDE CII (200 MG) Structure
PHENMETRAZINE HYDROCHLORIDE CII (200 MG) Chemical Properties
Melting point 175-177°C
storage temp. Controlled Substance, -20°C Freezer
solubility DMSO (Slightly), Methanol (Slightly), Water (Slightly, Sonicated)
form Solid
color White to Off-White
Safety Information
RIDADR 3249
HazardClass 6.1(b)
PackingGroup III
MSDS Information
PHENMETRAZINE HYDROCHLORIDE CII (200 MG) Usage And Synthesis
Chemical PropertiesWhite Solid
OriginatorPreludin, Boehringer Ingelheim, US ,1956
UsesAnorexic. Controlled substance (stimulant).
DefinitionChEBI: Phenmetrazine hydrochloride is an organic molecular entity.
Manufacturing Process10 grams of β-phenyl-α-methyl-β,β'-dihydroxy-diethylamine hydrochloride (produced by hydrogenation in the presence of palladium and charcoal of βphenyl-α-methyl-β-keto-β'-hydroxy-N-benzyl-diethylamine hydrochloride obtained from bromopropiophenone by reacting with benzyl-ethanolamine), are warmed with 10% hydrochloric acid for 6 hours on a water bath.After working up in the usual manner, the hydrochloride of the 2-phenyl-3methyl-morpholine crystallizes out from methanolic hydrochloric acid and acetone, MP = 182°C, according to US Patent 2,835,669.
Brand namePreludin (Boehringer Ingelheim).
Therapeutic FunctionAntiobesity
Safety ProfilePoison by ingestion, intravenous, intraperitoneal, and subcutaneous routes. Human reproductive effects. Human teratogenic effects by ingestion: developmental abnormalities of the respiratory and gastrointestinal systems, and effects on newborn including neonatal measures or effects. When heated to decomposition it emits very toxic fumes of NOx and HCl.
PHENMETRAZINE HYDROCHLORIDE CII (200 MG) Preparation Products And Raw materials
Raw materials2-Bromopropiophenone-->Hydrochloric acid-->Hydrogen-->N-Benzylethanolamine
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