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(6α,11β,16α,17α)-6,9-Difluoro-11-hydroxy-16-Methyl-spiro[androsta-1,4-diene-17,5'-[1,3]oxathiolane]-2',3,4'-trione

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(6α,11β,16α,17α)-6,9-Difluoro-11-hydroxy-16-Methyl-spiro[androsta-1,4-diene-17,5'-[1,3]oxathiolane]-2',3,4'-trione Suppliers list
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Products Intro: Product Name:Fluticasone USP Related Compound B
CAS:219719-95-6
Purity:0.99 Package:10mg;25mg;50mg;100mg
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Products Intro: Product Name:Fluticasone Related CoMpound B
CAS:219719-95-6
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Products Intro: Product Name:Fluticasone Related Compound B (Fluticasone Trioxo Impurity)
CAS:219719-95-6
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Products Intro: Product Name:Fluticasone Impurity 10（Fluticasone USP RC B）
CAS:219719-95-6
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Products Intro: Product Name:Fluticasone Trioxo Impurity
CAS:219719-95-6
Purity:>97% Package:25mg, 50 mg, 100 mg
(6α,11β,16α,17α)-6,9-Difluoro-11-hydroxy-16-Methyl-spiro[androsta-1,4-diene-17,5'-[1,3]oxathiolane]-2',3,4'-trione Basic information
Product Name:(6α,11β,16α,17α)-6,9-Difluoro-11-hydroxy-16-Methyl-spiro[androsta-1,4-diene-17,5'-[1,3]oxathiolane]-2',3,4'-trione
Synonyms:(6α,11β,16α,17α)-6,9-Difluoro-11-hydroxy-16-Methyl-spiro[androsta-1,4-diene-17,5'-[1,3]oxathiolane]-2',3,4'-trione;Fluticasone Related CoMpound B;Fluticasone USP RC B;Fluticasone Impurity 10(Fluticasone USP RC B);6alpha,9alpha-Difluoro-11beta-hydroxy-16alpha-methyl-2',3,4'-trioxo-17alpha-spiro(androsta-1,4-diene-17,5'-(1,3)oxathiolane);(5R,6'S,8'S,9'R,10'S,11'S,13'S,14'S,16'R)-6',9'-difluoro-11'-hydroxy-10',13',16'-trimethylspiro[1,3-oxathiolane-5,17'-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthrene]-2,3',4-trione;Fluticasone USP Related Compound B/Fluticasone Trioxo Impurity/6α,9α-Difluoro-11β-hydroxy-16α-methyl-2',3,4'-trioxo-17α-spiro(androsta-1,4-diene-17,5'-(1,3)oxathiolane);(5'R,6S,8S,9R,10S,11S,13S,14S,16R)
CAS:219719-95-6
MF:C22H24F2O5S
MW:438.48
EINECS:
Product Categories:Pharmaceuticals, Intermediates & Fine Chemicals, Steroids
Mol File:219719-95-6.mol
(6α,11β,16α,17α)-6,9-Difluoro-11-hydroxy-16-Methyl-spiro[androsta-1,4-diene-17,5'-[1,3]oxathiolane]-2',3,4'-trione Structure
(6α,11β,16α,17α)-6,9-Difluoro-11-hydroxy-16-Methyl-spiro[androsta-1,4-diene-17,5'-[1,3]oxathiolane]-2',3,4'-trione Chemical Properties
Melting point >125°C (dec.)
Boiling point 562.1±60.0 °C(Predicted)
density 1.43±0.1 g/cm3(Predicted)
storage temp. -20°C Freezer
solubility DMSO (Slightly), Methanol (Slightly, Sonicated)
form Solid
pka12.93±0.70(Predicted)
color Off-White to Pale Beige
Safety Information
MSDS Information
(6α,11β,16α,17α)-6,9-Difluoro-11-hydroxy-16-Methyl-spiro[androsta-1,4-diene-17,5'-[1,3]oxathiolane]-2',3,4'-trione Usage And Synthesis
UsesAn impurity of Fluticasone Propionate (F599500), a derivative of Flumethasone (F455000). An antiallergic; anti-asthmatic; anti-inflammatory. Fluticasone USP Related Compound B.
(6α,11β,16α,17α)-6,9-Difluoro-11-hydroxy-16-Methyl-spiro[androsta-1,4-diene-17,5'-[1,3]oxathiolane]-2',3,4'-trione Preparation Products And Raw materials
Tag:(6α,11β,16α,17α)-6,9-Difluoro-11-hydroxy-16-Methyl-spiro[androsta-1,4-diene-17,5'-[1,3]oxathiolane]-2',3,4'-trione(219719-95-6) Related Product Information
Fluticasone Finasteride 11-Oxo Fluticasone Propionate Fluticasone Fluticasone Acetate Fluticasone 5-Chloromethyl 6a,9a-Difluoro-11-hydroxy-16a-methyl-3-oxo-17a-(propionyloxy)-androsta-1,4-diene-17-carbothioate (6α,11β,16α,17α)-(6'α,11'β,16'α,17'α)-17,17'-(Trithiodicarbonyl)bis[6,9-difluoro-11-hydroxy-16-methyl-17-(1-oxopropoxy)-androsta-1,4-dien-3-one DesfluoroMethyl Fluticasone Propionate Disulfide Fluticasone IMpurity (1-oxopropoxy)-, S-(fluoromethyl)ester, (6α,11β,16α,17α)- (6a,11b,16a,17a)-6,9-Difluoro-11,17-dihydroxy-16-methyl-3-oxoandrosta-1,4-diene-17-carboxylic acid Fluticasone propionate Fluticasone propionate-d5 Fluticasone EP IMpurity B FLUTICASONE PROPIONATE INTERMEDIATE 5-Iodomethyl 6a,9a-Difluoro-11-hydroxy-16a-methyl-3-oxo-17a-(propionyloxy)-androsta-1,4-diene-17-carbothioate Ticabesone Propionate