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| | Butanedioic acid, methylene-, 4-octyl ester Basic information |
| Product Name: | Butanedioic acid, methylene-, 4-octyl ester | | Synonyms: | Butanedioic acid, methylene-, 4-octyl ester;Monooctyl Itaconate;4-Octyl itaconate;4-Octyl itaconate(CTK1B2911);2-Methylenebutanedioic acid 4-octyl ester;Itaconate;itaconate(CTK1B2911);Butanedioic acid, 2-methylene-, 4-octyl ester | | CAS: | 3133-16-2 | | MF: | C13H22O4 | | MW: | 242.32 | | EINECS: | | | Product Categories: | | | Mol File: | 3133-16-2.mol |  |
| | Butanedioic acid, methylene-, 4-octyl ester Chemical Properties |
| Boiling point | 377.2±25.0 °C(Predicted) | | density | 1.026±0.06 g/cm3(Predicted) | | storage temp. | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C | | solubility | DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 30 mg/ml | | form | A crystalline solid | | pka | 3.84±0.11(Predicted) |
| | Butanedioic acid, methylene-, 4-octyl ester Usage And Synthesis |
| Uses | 4-Octyl Itaconate increases nuclear factor erythroid 2-related factor 2 (Nrf2) protein levels and expression of Nrf2 target genes and enhances LPS-induced Nrf2 stabilization in mouse macrophages. In vivo, 4-octyl itaconate (50 mg/kg) decreases serum levels of IL-1β and TNF-α, increases Nrf2 protein expression, and protects against LPS-induced lethality in wild-type, but not Nrf2 knockout, mice. | | storage | Store at -20°C |
| | Butanedioic acid, methylene-, 4-octyl ester Preparation Products And Raw materials |
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