Company Name: |
Sigma-Aldrich
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Tel: |
021-61415566 800-8193336 |
Email: |
orderCN@merckgroup.com |
Products Intro: |
Product Name:Matrix Metalloproteinase-7 CAS:141256-52-2 Purity:~ 0.1mg/mL, Escherichia coli, buffered aqueous soluti Package:1pkg, 5μg, 10μg Remarks:M4565
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Company Name: |
Wuhan Chemstan Biotechnology Co., Ltd.
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Tel: |
027-65317797 15926423062 |
Email: |
422450190@qq.com |
Products Intro: |
Product Name:Human MMP7 Protein, Fc Tag Purity:>90% as determined by SDS-PAGE Package:50μg, 100μg
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Company Name: |
Shanghai Huzhen Industrial Co., LTD
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Tel: |
021-60345367 13916550749 |
Email: |
sales@shzbio.com |
Products Intro: |
Product Name:MMP7 CAS:141256-52-2 Purity:> 99% Package:50ul/RMB 1098;100ul/RMB 1880;200ul/RMB 2900 Remarks:Matrilysin; Matrilysin uterine; Matrin; Matrix Metalloproteinase 7; MMP-7; MMP 7; MMP7; MPSL1; PUMP 1; Pump 1 protease; PUMP1; Uterine Matrilysin; Uterine metalloproteinase; MMP7_H
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| MATRILYSIN Basic information |
Product Name: | MATRILYSIN | Synonyms: | Anti-MMP-7, C-Terminal antibody produced in rabbit;Pump-1 protease;Uterine metalloproteinase;PUMP-1;PUMP-1, ACTIVE, HUMAN, RECOMBINANT;RHMMP-7;RHMMP-7, ACTIVE;MMP-7 | CAS: | 141256-52-2 | MF: | | MW: | 0 | EINECS: | | Product Categories: | enzyme | Mol File: | Mol File | |
| MATRILYSIN Chemical Properties |
storage temp. | -70°C | form | buffered aqueous solution |
Hazard Codes | B | WGK Germany | 3 | HS Code | 3504009000 |
| MATRILYSIN Usage And Synthesis |
Uses | Matrix metalloproteinase-7 (MMP7) human has been used in in silico analysis of MMP-7 proteolysis of perlecan. | General Description | Matrix metalloproteinase-7 (MMP7) also referred to as matrilysin is encoded by the gene mapped to human chromosome 11q21-q22. MMP7 is a smallest member of MMP enzyme family and is highly expressed in cancer cells. MMP7 is exclusively released by epithelial cells. | Biochem/physiol Actions | Matrix metalloproteinase-7 (MMP-7) catalyzes the cleavage of extracellular matrix (ECM) proteins such as proteoglycans, fibronectin, entactin, laminin, collagen III/ IV/ V/ IX/ X/ XI, type I/ II/ IV/ V gelatins, and elastin. Matrix metalloproteinase-7 facilitates initial stages of tumor progression. Activated MMP7 plays a vital role in human colorectal cancer (CRC) liver metastases. Overexpression of MMP7 is observed in various human cancers, such as breast, lung, prostate, esophagus, stomach, endometrium, and ovarian carcinomas, as well as esophageal squamous cell carcinomas. Increased expression of MMP7 is also associated with pathogenesis of demyelinating multiple sclerosis (MS) lesions. Both in silico and in vitro studies show that MMP7 degrades glycosylated and basement membrane bound perlecan and plays a vital role in prostate cancer cell invasion. |
| MATRILYSIN Preparation Products And Raw materials |
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