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MedBioPharmaceutical Technology Inc
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Product Name:3-(5-[1,2]DITHIOLAN-3YL-PENTANOYLAMINO)-PROPYL-AMIDE
CAS:691410-93-2
Purity:98% Package:5mg; 10mg; 1mg Remarks:Medbio
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| Company Name: |
TargetMol Chemicals Inc.
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4008200310 |
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marketing@tsbiochem.com |
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Product Name:AN-7;AN7,AN 7
CAS:691410-93-2
Purity:98% Package:100 mg
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Shanghai Yifei Biotechnology Co. , Ltd.
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021-65675885 18964387627 |
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customer_service@efebio.com |
| Products Intro: |
Product Name:AN-7
CAS:691410-93-2
Purity:98% Package:1mg;5mg;10mg
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| | 3-(5-[1,2]DITHIOLAN-3YL-PENTANOYLAMINO)-PROPYL-AMIDE Basic information |
| Product Name: | 3-(5-[1,2]DITHIOLAN-3YL-PENTANOYLAMINO)-PROPYL-AMIDE | | Synonyms: | AN-7;3-(5-[1,2]DITHIOLAN-3YL-PENTANOYLAMINO)-PROPYL-AMIDE;5-(dithiolan-3-yl)-N-[3-[5-(dithiolan-3-yl)pentanoylamino]propyl]pentanamide;α-lipoic acid derivatives;AN7,AN 7;1,2-Dithiolane-3-pentanamide, N,N'-1,3-propanediylbis- | | CAS: | 691410-93-2 | | MF: | C19H34N2O2S4 | | MW: | 450.75 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![3-(5-[1,2]DITHIOLAN-3YL-PENTANOYLAMINO)-PROPYL-AMIDE Structure](StructureFile/ChemBookStructure9/GIF/CB9712795.gif) |
| | 3-(5-[1,2]DITHIOLAN-3YL-PENTANOYLAMINO)-PROPYL-AMIDE Chemical Properties |
| Melting point | 79-81 °C | | Boiling point | 702.1±43.0 °C(Predicted) | | density | 1.178±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMF: 10 mg/ml; DMSO: 20 mg/ml; DMSO:PBS (pH 7.2)(1:4): .15 mg/ml; Ethanol: 2 mg/ml | | form | A crystalline solid | | pka | 15.86±0.46(Predicted) |
| | 3-(5-[1,2]DITHIOLAN-3YL-PENTANOYLAMINO)-PROPYL-AMIDE Usage And Synthesis |
| Description | α-Lipoic acid is a cyclic disulfide antioxidant that interconverts with its reduced dithiol form. It is an essential cofactor for decarboxylation reactions of the citric acid cycle and acts as a general antioxidant.1 AN-7 is a more lipophilic analog of α-lipoic acid with enhanced potency and 1.5-fold increased maximal capacity to stimulate glucose transport into myocytes.2 This identifies the analogs of lipoic acid as potential new treatments for diabetes. | | References | 1. Biewenga, G.P., Haenen, G.R.M.M., and Bast, A. The pharmacology of the antioxidant lipoic acid Gen. Pharmacol. 29(3),315-331(1997).
2. Gruzman, A., Hidmi, A., Katzhendler, J., et al. Synthesis and characterization of new and potent α-lipoic acid derivatives Bioorg. Med. Chem. 12,1183-1190(2004). |
| | 3-(5-[1,2]DITHIOLAN-3YL-PENTANOYLAMINO)-PROPYL-AMIDE Preparation Products And Raw materials |
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