4-Aminobutyric acid NEW

Factory Supply 4-Aminobutyric acid CAS:56-12-2

Product Name:4-Aminobutyric acid

Synonyms:4-AMINOBUTANOIC ACID;4-AMINOBUTYRIC ACID;4-AMINO-N-BUTYRIC ACID;ALPHA-AMINOBUTANOIC ACID;AMINOBUTYRIC ACID, 4-;AMINOBUTYRIC-4 ACID;AURORA KA-1053;H-4-AMINOBUTYRIC ACID

CAS:56-12-2

MF:C4H9NO2

MW:103.12

EINECS:  200-258-6

Melting point:195 °C (dec.) (lit.)

Boiling point:248.0±23.0 °C(Predicted)

density:1.2300 (estimate)

Melting point:195 °C (dec.) (lit.)

Boiling point:248.0±23.0 °C(Predicted)

density:1.2300 (estimate)

Chemical Properties:4-Aminobutyric acid is a white flake or needle-like crystal; slightly odorous, deliquescence; easily soluble in water, slightly soluble in hot ethanol, insoluble in cold ethanol, ether and benzene; decomposition point is 202°C; LD50 (rat, abdominal cavity) 5400mg/kg.

Description

4-Aminobutyric acid (GABA) is the chief inhibitory neurotransmitter in the mammalian central nervous system. It plays a role in regulating neuronal excitability throughout the nervous system. In humans, GABA is also directly responsible for the regulation of muscle tone. Although chemically it is an amino acid, GABA is rarely referred to as such in the scientific or medical communities, because the term "amino acid," used without a qualifier, conventionally refers to the alpha amino acids, which GABA is not, nor is it ever incorporated into a protein. In spastic diplegia in humans, GABA absorption becomes impaired by nerves damaged from the condition's upper motor neuron lesion, which leads to hypertonia of the muscles signaled by those nerves that can no longer absorb GABA.