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Postion:Product Catalog >Organic Chemistry>Hydrocarbons and derivatives>Hydrocarbon halides>4-Fluorobenzyl bromide
4-Fluorobenzyl bromide
  • 4-Fluorobenzyl bromide

4-Fluorobenzyl bromide NEW

Price $100 $1
Package 1KG 1000KG
Min. Order: 1KG
Supply Ability: g-kg-tons, free sample is available
Update Time: 2023-12-26

Product Details

Product Name: 4-Fluorobenzyl bromide CAS No.: 459-46-1
Min. Order: 1KG Purity: 99%
Supply Ability: g-kg-tons, free sample is available Release date: 2023/12/26
Lead time: In stock Packaging: bottle/ drum/ bucket/ IBC, as request.
Delivery: By sea, by air, by express Origin: Manufacturer

1. Product information

Product Name:4-Fluorobenzyl bromide
Synonyms:P-FLUOROBENZYL BROMIDE;4-Fluoro-1-(bromomethyl)benzene;α-Bromo-4-fluorotoluene;4-Fluorobenzyl bromi;BroMobenzene of fluoride;Of fluoride broMide;1-(Bromomethyl)-4-fluorobenzene, alpha-Bromo-4-fluorotoluene;α-BroMo-p-fluorotoluene
CAS:459-46-1
MF:C7H6BrF
MW:189.02
EINECS:207-291-5
Product Categories:Benzyl;Fluoro-contained benzyl bromide series;Fluorinated benzene series;alkyl bromide|alkyl Fluorine;Halogenated Heterocycles ,Pyrimidines;bc0001
Mol File:459-46-1.mol
Article illustration

4-Fluorobenzyl bromide Chemical Properties
Boiling point 85 °C15 mm Hg(lit.)
density 1.517 g/mL at 25 °C(lit.)
refractive index n20/D 1.547(lit.)
Fp >230 °F
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
solubility soluble in Chloroform
form Liquid
Specific Gravity1.517
color Clear colorless to yellow
Sensitive Lachrymatory
4-Fluorobenzyl bromide Usage And Synthesis
Chemical Properties

4-Fluorobenzyl bromide (C7H6BrF, CAS registry No. 459-46-1) is a colorless to light yellow liquid. Its flash point is 74.8 oC. It is stable at room temperature in closed containers under normal storage and handling conditions. 1,3-Difluorobenzene can react with water to form toxic fumes. Therefore, it should be stored in a tightly closed container and should be stored in a cool, dry and well-ventilated area away from incompatible substances.

Uses

4-Fluorobenzyl bromide is an important intermediate in organic chemistry. 4-Fluorobenzyl bromide can be used as alkylating reagent to participate in the alkylation reaction with sulfamic esters (R-O-SO2-NH2) in liquid-liquid phase transfer conditions, resulting in the preparation of the N-dialkyled products or the corresponding ethers by scission of the O-SO2 bond, depending on the nature of R.
4-Fluorobenzyl bromide can be used for the synthesis of glycyrrhetinic acid (GA) derivatives, which are slow-binding inhibitors of tyrosinase and have inhibitory effects on melanogenesis.

Chemical PropertiesColorless to light yellow liqui
Uses4-Fluorobenzyl Bromide is a substituted benzyl bromide reagent used in the preparation of wide range of biologically active compounds such as bronchodialators, neurochemicals and antibacterials.
Uses4-Fluorobenzyl bromide was used in the preparation of:
  • 3-acetyl-1-(4-fluorobenzyl)-4-hydroxy-1H-indole

  • 1-(4-fluorobenzyl)-5-(pyrrolidine-1-sulfonyl)isatin

  • (S)-1-(4-fluorobenzyl)-5-(2-(4-fluorophenoxymethyl)pyrrolidine-1-sulfonyl)isatin

  • 8-bromo 9-(4-fluorobenzyl) adenine

  • 8-bromo 3-(4-fluorobenzyl) adenine


2. Packaging

For powders: normal is 25kgs/Drum or bag, or larger/smaller package as request.

For liquids: normal 25kgs/drum, 180-300kgs/bucket, or IBC, determined by the nature of the product. 

                     Or smaller package 1kg/bottle, 10kgs/bottle as request. 


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3. Shipping

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4. Contact information

For more details, pls contact us freely.

Email address : elin@fdachem.com

Mob: 86 13613820652 

WhatsApp/Skype/Wechat/LINE: 86 13613820652

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Company Profile Introduction

Henan Fengda Chemical Co., Ltd. is located in the High-tech Development Zone of Henan Province. Specializing in the production and sales of various fine chemical products required for industrial production, including chemical raw materials, organic raw materials, petrochemicals, chemical reagents, solvents, catalysts, and additives, etc.

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