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Postion:Product Catalog >Biochemical Engineering>Plant extracts>GAMBOGIC ACID
GAMBOGIC ACID
  • GAMBOGIC ACID

GAMBOGIC ACID

Price $1
Package 1kg
Min. Order: 1g
Supply Ability: 100KG
Update Time: 2019-07-06

Product Details

Product Name: GAMBOGIC ACID CAS No.: 2752-65-0
Min. Order: 1g Purity: 99%
Supply Ability: 100KG Release date: 2019/07/06
Product:: AD68
GAMBOGIC ACID Basic information
Product Name: GAMBOGIC ACID
Synonyms: BETA-GUTTIFERIN;BETA-GUTTILACTONE;GAMBOGIC ACID;GUTTATIC ACID;GUTTIC ACID;(z)-methyl-3-pentenyl)-;1,5-methano-1h,3h,11h-furo(3,4-g)pyrano(3,2-b)xanthene-1-crotonicacid,3a,4,5,;3,3,11-tetramethyl-13-(3-methyl-2-butenyl)-11-(4-7-tetrahydro-8-hydroxy-alph
CAS: 2752-65-0
MF: C38H44O8
MW: 628.75
EINECS:  
Product Categories: chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;Inhibitors
Mol File: 2752-65-0.mol
Article illustration
 
GAMBOGIC ACID Chemical Properties
Melting point  88.5°C
Boiling point  586.06°C (rough estimate)
alpha  D20 -685° (methanol)
density  1.1057 (rough estimate)
refractive index  1.5290 (estimate)
storage temp.  Store at -20°C
solubility  DMSO: ≥10mg/mL
color  yellow to orange
InChIKey GEZHEQNLKAOMCA-XKZIYDEJSA-N
 
Safety Information
Hazard Codes  T
Risk Statements  25-36/37/38
Safety Statements  26-45
RIDADR  UN 2811 6.1 / PGIII
RTECS  PB9268200
MSDS Information
 
 
GAMBOGIC ACID Usage And Synthesis
Uses antiinflammatory, cytotoxic, inhibits HeLa cells in vitro;
Definition ChEBI: A natural product found in Garcinia hanburyi.
Biological Activity Natural product isolated from the Garcinia hanburyi tree. Induces apoptosis in several tumor cell lines including T47D cells. Activates caspases with an EC 50 value of 0.78-1.64 μ M and competitively inhibits antiapoptotic Bcl-2 family proteins (IC 50 values are 1.47, 1.21, 2.02, 0.66, 1.06 and 0.79 μ M for Bcl-XL, Bcl-2, Bcl-W, Bcl-B, Bfl-1 and Mcl-1 respectively). Also blocks K IR 2.1 channels (EC 50 ≤ 100 nM).

Company Profile Introduction

Established in 2014,Career Henan Chemical Co. is a manufacturerspecializing in the sale of fine chemicals. Mainly deals in the sales of: Pharmaceutical intermediates OLED intermediates: Pharmaceutical intermediates; OLED intermediates;

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