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Postion:Product Catalog >API>Vitamins and Minerals medicines>Vitamin B drugs>Hydroxocobalamin Chloride
Hydroxocobalamin Chloride
  • Hydroxocobalamin Chloride
  • Hydroxocobalamin Chloride
  • Hydroxocobalamin Chloride
  • Hydroxocobalamin Chloride
  • Hydroxocobalamin Chloride

Hydroxocobalamin Chloride NEW

Price Get Latest Price
Package 10G
Min. Order: 1G
Supply Ability: 100kg
Update Time: 2024-04-08

Product Details

Product Name: Hydroxocobalamin Chloride CAS No.: 58288-50-9
EC-No.: 261-200-3 Min. Order: 1G
Purity: 99% Supply Ability: 100kg
Release date: 2024/04/08

Manufacturer Provide Vitamin B12 Hydroxycobalamin HCl CAS 58288-50-9 Hydroxocobalamin Chloride


Article illustration

Introduction

Name: Hydroxocobalamin Chloride

C.A.S NO. : 58288-50-9
Chemical name: Vitamin B12 Hydroxycobalamin HCl 

Assay (%)(HPLC, Basis on drying):99%

Molecular formula: C62H89ClCoN13O15P

Appearance: Dark Red Crystals or Crystalline Powder

Storage Condition: Store in cool and dry places ,keep away from strong light 


Hydroxocobalamin, also known as hydroxycobalamin, is a member of the class of compounds known as cobalamin derivatives. These organic compounds contain a corrin ring, a cobaltatom, and a nucleotide moiety. Cobalamin derivatives are actually derived from vitamin B12. Hydroxocobalamin is practically insoluble (in water) and a moderately acidic compound (based on its pKa). Hydroxocobalamin is formally rated as a possibly carcinogenic (IARC 2B) potentially toxic compound. Hydroxocobalamin is a drug used in the treatment of pernicious anemia and in the prevention and treatment of vitamin B12 deficiency arising from alcoholism, malabsorption, tapeworm infestation, celiac disease, hyperthyroidism, hepatic-biliary tract disease, persistent diarrhea, ileal resection, pancreatic cancer, renal disease, prolonged stress, vegan diets, macrobiotic diets, and other restrictive diets. Hydroxocobalamin is also used in the treatment of known or suspected cyanide poisoning.


Use
1) Hydroxocobalamin is commonly used to address vitamin B-12 deficiency.
2) Hydroxocobalamin received approval for use as a treatment for cyanide poisoning. 
3) Hydroxocobalamin has been identified as a scavenger of nitric oxide, an essential muscle regulator that also acts as a free radical.


ItemSpecificationTest ResultsTesting methods
AppearanceDark red, crystals or crystalline powderCompliesMonograph:0547
Visual method
Identifiction AUV:Absorption maxima at 274±1nm,351±1nm and 525±2nm.274±1nm,351±1nm,525±2nmCompliesPh.Eur.monograph Ph.Eur.
<2.2.25>
A274nm/A351nm: 0.75~0.83
A525nm/A351nm: 0.31~0.35
0.79
0.33
Identifiction B
 
TLC:The principal spot in the
chromatogram obtained with the test
solution is similar in position,colour and
size to the principal spot in the
chromatogram obtained with the
reference solution
Complies
 
Ph.Eur.monograph Ph.Eur.
<2.2.27>
Identifiction CChlorides:It gives reaction(a) of chloridesCompliesPh.Eur.monograph<2.3.1>Chlorides
Loss on drying8.0%~12.0%8.4%Ph.Eur.monograph Ph.Eur<2.2.32>
Assay96.0%~102.0%98.8%Ph.Eur.monograph Ph.Eur<2.2.25>
Related substances≤5%2%Ph.Eur.monograph/ Ph.Eur<2.2.29>(HPLC)
Acetone≤5000ppm22ppmIn house/(GC)
(GC)SOP-QC-158-04-03
Total aerobic microbial count≤1000cfu/g<10cfu/gChP 2015<1105>
The total combined
yeasts/mould count
≤100cfu/g<10cfu/g

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Company Profile Introduction

Shaanxi TNJONE Pharmaceutical Co., Ltd supplies more than 2,000 kinds of products, covering the whole field of health industry, including human APIs, veterinary APIs, food additives, natural nutrition ingredients, feed additives, cosmetic additives, intermediates etc. With global sourcing advantages, the group is fully capable of meeting the one-stop sourcing needs of global customers. Today, Shaanxi TNJONE Pharmaceutical Co., Ltd.'s marketing network has spread over more than 100 countries and regions on five continents, providing professional service for global customers.

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Shaanxi TNJONE Pharmaceutical Co., Ltd

1YR ChinaChina
  • Since: 2019-05-23
  • Address: No. 4C-11-A392, Financial Port, Northwest corner of Fengjing Avenue and Fengxin Road, Fengdong New C
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