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o-Sialic acid(131-48-6)

o-Sialic acid(131-48-6)
Product IdentificationBack to Contents
【Product Name】

o-Sialic acid
【Synonyms】

(2S,4S,5R,6R)-5-Acetamido-2,4-dihydroxy-6-(1,2,3-trihydroxypropyl)oxane-2-carboxylic acid
5-N-Acetyl-D-neuraminic acid
D-glycero-D-galacto-Nonulosonic acid, 5-acetamido-3,5-dideoxy-
N-Acetylneuraminic acid
N-Acetylsialic acid
Sialomucin
【CAS】

131-48-6
【Formula】

C11H19NO9
【Molecular Weight】

309.27
【EINECS】

205-023-1
【Merck】

12,8628
【Beilstein/Gmelin】

1716283
【Beilstein Reference】

4-04-00-03288
Physical and Chemical PropertiesBack to Contents
【Solubility in water】

Very soluble
【Melting Point】

185 - 187
【pKa/pKb】

2.41 (pKa)
【Partition Coefficient】

-3.19
【Usage】

An n-acyl derivative of neuraminic acid. N-acetylneuraminic acid occurs in many polysaccharides, glycoproteins, and glycolipids in animals and bacteria.
First Aid MeasuresBack to Contents
【Ingestion】

Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
【Inhalation】

Remove from exposure to fresh air immediately.
【Skin】

Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
【Eyes】

Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids.
Handling and StorageBack to Contents
【Storage】

Store in a cool, dry place. Keep container closed when not in use. Deep freeze (below -20 C).
【Handling】

Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Avoid contact with eyes, skin, and clothing. Avoid ingestion and inhalation.
Exposure Controls/Personal ProtectionBack to Contents
【Personal Protection】

Eyes: Wear safety glasses and chemical goggles if splashing is possible. Skin: Wear appropriate protective gloves and clothing to prevent skin exposure. Clothing: Wear appropriate protective clothing to minimize contact with skin.
【Respirators】

Wear a NIOSH/MSHA or European Standard EN 149 approved full-facepiece airline respirator in the positive pressure mode with emergency escape provisions.
【Exposure Effects】

The toxicological properties of this material have not been investigated.
Fire Fighting MeasuresBack to Contents
【Flash Point】

184
【Fire Fighting】

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. To extinguish fire, use water, dry chemical, chemical foam, or alcohol-resistant foam.
Accidental Release MeasuresBack to Contents
【Small spills/leaks】

Clean up spills immediately, using the appropriate protective equipment. Sweep up, then place into a suitable container for disposal.
Stability and ReactivityBack to Contents
【Stability】

Stable under normal temperatures and pressures.
【Incompatibilities】

Strong oxidizing agents.
【Decomposition】

Irritating and toxic fumes and gases.
Hazards IdentificationBack to Contents
【EC Safety Phrase】

S 22 24/25
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