ChemicalBook >>Acrivastine>>Acrivastine(87848-99-5)

Acrivastine(87848-99-5)

Acrivastine(87848-99-5)
Product IdentificationBack to Contents
【Product Name】

Acrivastine
【Synonyms】

(E)-3-[6-[(E)-1-(4-Methylphenyl)-3-pyrrolidin-1-yl-prop-1-enyl]pyridin-2-yl]prop-2-enoic acid
【CAS】

87848-99-5
【Formula】

C22H24N2O2
【Molecular Weight】

348.44
【Merck】

12,129
Physical and Chemical PropertiesBack to Contents
【Solubility in water】

Insoluble
【Vapor Pressure】

3.7E-13 (25 C)
【Density】

1.17 g/cm3 (20 C)
【pKa/pKb】

1.99 (pKa)
【Partition Coefficient】

4.55
【Usage】

This material is a histamine antagonist (h1 sub-type). It is an agent intended for the treatment of allergic rhinitis.
First Aid MeasuresBack to Contents
【Ingestion】

Never attempt to induce vomiting. Do not attempt to give any solid or liquid by mouth if the exposed subject is unconscious or semi-conscious. Wash out the mouth with water. If the exposed subject is fully conscious, give plenty of water to drink. Obtain medical attention.
【Inhalation】

Physical form suggests that risk of inhalation exposure is negligible.
【Skin】

Using appropriate personal protective equipment, remove contaminated clothing and flush exposed area with large amounts of water. Obtain medical attention if skin reaction occurs, which may be immediate or delayed.
【Eyes】

Wash immediately with clean and gently flowing water. Continue for at least 15 minutes. Obtain medical attention.
Handling and StorageBack to Contents
【Storage】

No storage requirements necessary for occupational hazards. Follow product information storage instructions to maintain efficacy.
Exposure Controls/Personal ProtectionBack to Contents
【Personal Protection】

Wear approved safety glasses with side shields if eye contact is possible.
【Exposure Effects】

Exposure might occur via ingestion; skin; eyes. Possible effects of overexposure in the workplace include: sedation; irritation; swelling; redness; itching; pain.
Accidental Release MeasuresBack to Contents
【Small spills/leaks】

Collect and place it in a suitable, properly labeled container for recovery or disposal. Water can be used for clean-up and decontamination operations
Stability and ReactivityBack to Contents
【Stability】

Stable at normal temperatures and pressures.
Fire Fighting MeasuresBack to Contents
【Fire Potential】

Expected to be non-combustible.
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