Chemical Safety Data Sheet MSDS / SDS

2-Butoxyethanol

Revision Date:2024-03-16Revision Number:1

SECTION 1: Identification of the substance/mixture and of the company/undertaking

Product identifier

Product name: 2-Butoxyethanol
CBnumber: CB9719325
CAS: 111-76-2
EINECS Number: 203-905-0
Synonyms: butyl glycol,Ethylene glycol monobutyl ether

Relevant identified uses of the substance or mixture and uses advised against

Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
Uses advised against: none

Company Identification

Company: Chemicalbook
Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
Telephone: 400-158-6606

SECTION 2: Hazards identification

GHS Label elements, including precautionary statements

Symbol(GHS)

Signal wordWarning

Precautionary statements

P201 Obtain special instructions before use.

P202 Do not handle until all safety precautions have been read and understood.

P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P260 Do not breathe dust/fume/gas/mist/vapours/spray.

P261 Avoid breathing dust/fume/gas/mist/vapours/spray.

P264 Wash hands thoroughly after handling.

P264 Wash skin thouroughly after handling.

P270 Do not eat, drink or smoke when using this product.

P271 Use only outdoors or in a well-ventilated area.

P280 Wear protective gloves/protective clothing/eye protection/face protection.

P284 Wear respiratory protection.

P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P307+P311 IF exposed: call a POISON CENTER or doctor/physician.

P337+P313 IF eye irritation persists: Get medical advice/attention.

P403+P233 Store in a well-ventilated place. Keep container tightly closed.

P405 Store locked up.

P501 Dispose of contents/container to..…

Hazard statements

H227 Combustible liquid

H302 Harmful if swallowed

H312 Harmful in contact with skin

H315 Causes skin irritation

H319 Causes serious eye irritation

H330 Fatal if inhaled

H332 Harmful if inhaled

H335 May cause respiratory irritation

H361 Suspected of damaging fertility or the unborn child

H370 Causes damage to organs

H373 May cause damage to organs through prolonged or repeated exposure

SECTION 3: Composition/information on ingredients

Substance

Product name: 2-Butoxyethanol
Synonyms: butyl glycol,Ethylene glycol monobutyl ether
CAS: 111-76-2
EC number: 203-905-0
MF: C6H14O2
MW: 118.17

SECTION 4: First aid measures

Description of first aid measures

General advice

Show this material safety data sheet to the doctor in attendance.

If inhaled

After inhalation: fresh air. If breathing stops: mouth-to-mouth breathing or artificial respiration. Oxygen if necessary. Immediately call in physician.

In case of skin contact

In case of skin contact: Take off immediately all contaminated clothing. Rinse skin with water/ shower.

In case of eye contact

After eye contact: rinse out with plenty of water. Call in ophthalmologist. Remove contact lenses.

If swallowed

After swallowing: caution if victim vomits. Risk of aspiration! Keep airways free. Pulmonary failure possible after aspiration of vomit. Call a physician immediately.

Most important symptoms and effects, both acute and delayed

The most important known symptoms and effects are described in the labelling (see section 2.2) and/or in section 11

Indication of any immediate medical attention and special treatment needed

No data available

SECTION 5: Firefighting measures

Extinguishing media

Suitable extinguishing media

Carbon dioxide (CO2) Foam Dry powder

Unsuitable extinguishing media

For this substance/mixture no limitations of extinguishing agents are given.

Special hazards arising from the substance or mixture

Carbon oxides Combustible.

Vapors are heavier than air and may spread along floors. Forms explosive mixtures with air on intense heating.

Development of hazardous combustion gases or vapours possible in the event of fire.

Advice for firefighters

Stay in danger area only with self-contained breathing apparatus. Prevent skin contact by keeping a safe distance or by wearing suitable protective clothing.

Further information

Remove container from danger zone and cool with water. Prevent fire extinguishing water from contaminating surface water or the ground water system.

NFPA 704

HEALTH	3	Short exposure could cause serious temporary or moderate residual injury (e.g. liquid hydrogen, sulfuric acid, calcium hypochlorite, hexafluorosilicic acid)
FIRE	2	Must be moderately heated or exposed to relatively high ambient temperature before ignition can occur and multiple finely divided suspended solids that do not require heating before ignition can occur. Flash point between 37.8 and 93.3 °C (100 and 200 °F). (e.g. diesel fuel, sulfur)
REACT	0	Normally stable, even under fire exposure conditions, and is not reactive with water (e.g. helium,N2)
SPEC. HAZ.

SECTION 6: Accidental release measures

Personal precautions, protective equipment and emergency procedures

Advice for non-emergency personnel: Do not breathe vapors, aerosols. Avoid substance contact. Ensure adequate ventilation. Keep away from heat and sources of ignition.

Evacuate the danger area, observe emergency procedures, consult an expert. For personal protection see section 8.

Environmental precautions

Do not let product enter drains.

Methods and materials for containment and cleaning up

Cover drains. Collect, bind, and pump off spills. Observe possible material restrictions (see sections 7 and 10). Take up with liquid-absorbent material (e.g. Chemizorb? ). Dispose of properly. Clean up affected area.

Reference to other sections

For disposal see section 13.

SECTION 7: Handling and storage

Precautions for safe handling

Advice on safe handling

Work under hood. Do not inhale substance/mixture. Avoid generation of vapours/aerosols.

Advice on protection against fire and explosion

Keep away from open flames, hot surfaces and sources of ignition.Take precautionary measures against static discharge.

Hygiene measures

Immediately change contaminated clothing. Apply preventive skin protection. Wash hands and face after working with substance.

For precautions see section 2.2.

Conditions for safe storage, including any incompatibilities

Storage conditions

Tightly closed.

Specific end use(s)

Apart from the uses mentioned in section 1.2 no other specific uses are stipulated

SECTION 8: Exposure controls/personal protection

control parameter

Hazard composition and occupational exposure limits

Does not contain substances with occupational exposure limits.

Exposure controls

Personal protective equipment

Eye/face protection

Use equipment for eye protection tested and approved under appropriate

government standards such as NIOSH (US) or EN 166(EU). Safety glasses

Skin protection

This recommendation applies only to the product stated in the safety data sheet, supplied by us and for the designated use. When dissolving in or mixing with other substances and under conditions deviating from those stated in EN374 please contact the supplier of CE-approved gloves (e.g. KCL GmbH, D-36124 Eichenzell, Internet: www.kcl.de).

Full contact

Material: butyl-rubber

Minimum layer thickness: 0,7 mm Break through time: 480 min Material tested:Butoject? (KCL 898)

Splash contact Material: Nitrile rubber

Minimum layer thickness: 0,4 mm Break through time: 120 min

Material tested:Camatril? (KCL 730 / Aldrich Z677442, Size M)

Body Protection

protective clothing

Respiratory protection

Recommended Filter type: Filter A (acc. to DIN 3181) for vapours of organic compounds

The entrepeneur has to ensure that maintenance, cleaning and testing of respiratory protective devices are carried out according to the instructions of the producer.

These measures have to be properly documented.

Control of environmental exposure

Do not let product enter drains.

Exposure limits

TLV-TWA skin 25 ppm (121 mg/m³) (ACGIH), 50 ppm (242 mg/m³) (OSHA); STEL 75 ppm (363 mg/m³) (ACGIH);IDLH 700 ppm (NIOSH). .

SECTION 9: Physical and chemical properties

Information on basic physicochemical properties

Appearancecolorless liquid
Odourether-like, mild, sweet
Odour Threshold0,1 ppm
pH7 at 20 °C (as aqueous solution)
Melting point/freezing pointMelting point/range: -75 °C - lit.
Initial boiling point and boiling range169 - 172,5 °C - lit.
Flash point67 °C - Pensky-Martens closed cup - DIN 51758
Evaporation rateNo data available
Flammability (solid, gas)Not applicable
Upper/lower flammability or explosive limitsUpper explosion limit: 12,7 %(V) Lower explosion limit: 1,1 %(V)
Vapour pressure <1 mm Hg ( 20 °C)
Vapour density 4,08 - (Air = 1.0)
Relative densityNo data available
Water solubility900g/l completely miscible
Partition coefficient: n-octanol/waterlog Pow: 0,81 at 25 °C - Bioaccumulation is not expected., (ECHA)
Autoignition temperature230 °C at 1.013,25 hPa - DIN 51794
Decomposition temperatureDistillable in an undecomposed state at normal pressure.
ViscosityViscosity, kinematic: 3,642 mm2/s at 20 °C2,284 mm2/s at 40 °C Viscosity, dynamic: 3,6 mPa.s at 20 °C
Explosive propertiesNo data available
Oxidizing propertiesNo data available
Henry's Law Constant(x 10^-6 atm?m³/mol): 2.36 (approximate - calculated from water solubility and vapor pressure)
λmaxλ: 230 nm Amax: 1.0
λ: 250 nm Amax: 0.10
λ: 275 nm Amax: 0.05
λ: 300-400 nm Amax: 0.01

Other safety information

Surface tension 65,03 mN/m at 2g/l at 20 °C

Relative vapor 4,08 - (Air = 1.0)

density

SECTION 10: Stability and reactivity

Reactivity

Forms explosive mixtures with air on intense heating.

A range from approx. 15 Kelvin below the flash point is to be rated as critical.

Chemical stability

The product is chemically stable under standard ambient conditions (room temperature) .

Possibility of hazardous reactions

Violent reactions possible with:

Strong oxidizing agents

Generates dangerous gases or fumes in contact with:

Aluminum

Conditions to avoid

Strong heating.

Incompatible materials

No data available

Hazardous decomposition products

In the event of fire: see section 5

SECTION 11: Toxicological information

Information on toxicological effects

Acute toxicity

LD50 Oral - Guinea pig - male and female - 1.414 mg/kg (OECD Test Guideline 401)
Remarks: Classified according to Regulation (EU) 1272/2008, Annex VI (Table 3.1/3.2)
Acute toxicity estimate Inhalation - 11,1 mg/l (Expert judgment)
Remarks: (Regulation (EC) No 1272/2008, Annex VI) Acute toxicity estimate Inhalation - 11,1 mg/l (Expert judgment)
Remarks: (Regulation (EC) No 1272/2008, Annex VI) LC0 Inhalation - Guinea pig - 633 ppm
LD50 Dermal - Guinea pig - male and female - > 2.000 mg/kg (OECD Test Guideline 402)
Remarks: (ECHA)

Skin corrosion/irritation

Skin - Rabbit
Result: Irritating to skin. - 4 h
(Regulation (EC) No. 440/2008, Annex, B.4) Remarks: (ECHA)
(Regulation (EC) No 1272/2008, Annex VI)

Serious eye damage/eye irritation

Eyes - Rabbit
Result: Irritating to eyes. - 24 h
(OECD Test Guideline 405)
(Regulation (EC) No 1272/2008, Annex VI)

Respiratory or skin sensitization

(OECD Test Guideline 406)

Germ cell mutagenicity

Test Type: Ames test
Test system: Salmonella typhimurium
Metabolic activation: with and without metabolic activation Method: OECD Test Guideline 471
Result: negative
Test Type: Mutagenicity (mammal cell test): chromosome aberration. Test system: Chinese hamster ovary cells
Metabolic activation: with and without metabolic activation Method: OECD Test Guideline 473
Result: negative
Test Type: In vitro mammalian cell gene mutation test Test system: Chinese hamster ovary cells
Metabolic activation: with and without metabolic activation Method: OECD Test Guideline 476
Result: negative
Test Type: Micronucleus test Species: Mouse
Cell type: Red blood cells (erythrocytes) Application Route: Intraperitoneal Method: OECD Test Guideline 474 Result: negative

Carcinogenicity

No data available

Reproductive toxicity

Overexposure may cause reproductive disorder(s) based on tests with laboratory animals.

Specific target organ toxicity - single exposure

No data available

Specific target organ toxicity - repeated exposure

No data available

Aspiration hazard

No data available

Toxicity

LD50 orally in rats: 1.48 g/kg (Smyth)

SECTION 12: Ecological information

Toxicity

Toxicity to fish

static test LC50 - Oncorhynchus mykiss (rainbow trout) - 1.474 mg/l

- 96 h

(OECD Test Guideline 203)

Toxicity to daphnia and other aquatic invertebrates

static test EC50 - Daphnia magna (Water flea) - 1.550 mg/l - 48 h (OECD Test Guideline 202)

Toxicity to algae

static test ErC50 - Pseudokirchneriella subcapitata (green algae) - 1.840 mg/l - 72 h

(OECD Test Guideline 201)

Toxicity to bacteria

static test - Pseudomonas putida - 700 mg/l - 16 h

Persistence and degradability

Biodegradability aerobic - Exposure time 28 d

Result: 90,4 % - Readily biodegradable. (OECD Test Guideline 301B)

Ratio BOD/ThBOD 88 %

Bioaccumulative potential

No data available

Mobility in soil

No data available

Results of PBT and vPvB assessment

This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.

Other adverse effects

No data available

SECTION 13: Disposal considerations

Waste treatment methods

Product

See www.retrologistik.com for processes regarding the return of chemicals and

containers, or contact us there if you have further questions.

Incompatibilities

May form explosive mixture with air. Can form unstable and explosive peroxides; check for peroxides prior to distillation; render harmless if positive. Decomposes, producing toxic fumes. Violent reaction with strong caustics and strong oxidizers. Attacks some coatings, plastics and rubber. Attacks metallic aluminum at high temperatures.

Waste Disposal

EGBE is destroyed by burning in an incinerator. In the laboratory, small amounts may be disposed of in the sink with a large volume of water.

SECTION 14: Transport information

UN number

ADR/RID: - IMDG: - IATA: -

UN proper shipping name

ADR/RID: Not dangerous goods IMDG: Not dangerous goods IATA: Not dangerous goods

Transport hazard class(es)

ADR/RID: - IMDG: - IATA: -

Packaging group

ADR/RID: - IMDG: - IATA: -

Environmental hazards

ADR/RID: no IMDG Marine pollutant: no IATA: no

Special precautions for user

No data available

SECTION 15: Regulatory information

Safety, health and environmental regulations/legislation specific for the substance or mixture

Regulations on the Safety Management of Hazardous Chemicals

China Catalog of Hazardous chemicals 2015:Listed. website: https://www.mem.gov.cn/

Measures for Environmental Management of New Chemical Substances

Korea Existing Chemicals List (KECL):Listed. website: http://ncis.nier.go.kr

New Zealand Inventory of Chemicals (NZIoC):Listed. website: https://www.epa.govt.nz/

Vietnam National Chemical Inventory:Listed. website: https://chemicaldata.gov.vn/

EC Inventory:Listed.

Philippines Inventory of Chemicals and Chemical Substances (PICCS):Listed. website: https://emb.gov.ph/

Chinese Chemical Inventory of Existing Chemical Substances (China IECSC):Listed. website: https://www.mee.gov.cn/

European Inventory of Existing Commercial Chemical Substances (EINECS):Listed. website: https://echa.europa.eu/

United States Toxic Substances Control Act (TSCA) Inventory:Listed. website: https://www.epa.gov/

SECTION 16: Other information

Abbreviations and acronyms

CAS: Chemical Abstracts Service
ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
IMDG: International Maritime Dangerous Goods
IATA: International Air Transportation Association
TWA: Time Weighted Average
STEL: Short term exposure limit
LC50: Lethal Concentration 50%
LD50: Lethal Dose 50%
EC50: Effective Concentration 50%

References

【1】CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple

【2】ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp

【3】ECHA - European Chemicals Agency, website: https://echa.europa.eu/

【4】eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en

【5】ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg

【6】Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp

【7】HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm

【8】IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/

【9】IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home

【10】Sigma-Aldrich, website: https://www.sigmaaldrich.com/

Other Information

Check for peroxides prior to distillation; eliminate if found.

Disclaimer:

The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.