BERYLLIUM OXIDE
Product identifier
- Product name: BERYLLIUM OXIDE
- CBnumber: CB3118746
- CAS: 1304-56-9
- EINECS Number: 215-133-1
- Synonyms: beryllium oxide,BROMELLITE
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
- Uses advised against: none
Company Identification
- Company: Chemicalbook
- Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
- Telephone: 400-158-6606
Classification of the substance or mixture
Acute toxicity - Category 3, Oral
Skin irritation, Category 2
Eye irritation, Category 2
Skin sensitization, Category 1
Acute toxicity - Category 2, Inhalation
Specific target organ toxicity – single exposure, Category 3
Specific target organ toxicity – repeated exposure, Category 1
Carcinogenicity, Category 1B
Label elements
Pictogram(s)
- Signal wordDanger
H301 Toxic if swalloed
H315 Causes skin irritation
H317 May cause an allergic skin reaction
H319 Causes serious eye irritation
H330 Fatal if inhaled
H335 May cause respiratory irritation
H350 May cause cancer
H372 Causes damage to organs through prolonged or repeated exposure
P201 Obtain special instructions before use.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P284 Wear respiratory protection.
P320 Specific treatment is urgent (see … on this label).
P330 Rinse mouth.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405 Store locked up.
P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P272 Contaminated work clothing should not be allowed out of the workplace.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P271 Use only outdoors or in a well-ventilated area.
P284 [In case of inadequate ventilation] wear respiratory protection.
P203 Obtain, read and follow all safety instructions before use.
P301+P316 IF SWALLOWED: Get emergency medical help immediately.
P321 Specific treatment (see ... on this label).
P330 Rinse mouth.
P302+P352 IF ON SKIN: Wash with plenty of water/...
P332+P317 If skin irritation occurs: Get medical help.
P362+P364 Take off contaminated clothing and wash it before reuse.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P333+P317 If skin irritation or rash occurs: Get medical help.
P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P316 Get emergency medical help immediately.
P320 Specific treatment is urgent (see ... on this label).
P319 Get medical help if you feel unwell.
P318 IF exposed or concerned, get medical advice.
P405 Store locked up.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards
no data available
Substance
- Product name: BERYLLIUM OXIDE
- Synonyms: beryllium oxide,BROMELLITE
- CAS: 1304-56-9
- EC number: 215-133-1
- MF: BeO
- MW: 25.01
Description of first aid measures
If inhaledFresh air, rest. Half-upright position. Refer for medical attention.
Remove contaminated clothes. Rinse skin with plenty of water or shower. Wear protective gloves when administering first aid.
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Rinse mouth. Refer for medical attention .
Most important symptoms and effects, both acute and delayed
Any dramatic, unexplained weight loss should be considered as possible first indication of beryllium disease. Other symptoms include anorexia, fatigue, weakness, malaise. Inhalation causes pneumonitis, nasopharyngitis, tracheobronchitis, dyspnea, chronic cough. Contact with dust causes conjunctival inflammation of eyes and irritation of skin. (USCG, 1999)
Indication of any immediate medical attention and special treatment needed
Immediate first aid: Ensure that adequate decontamination has been carried out. If patient is not breathing, start artificial respiration, preferably with a demand-valve resuscitator, bag-valve-mask device, or pocket mask, as trained. Perform CPR as necessary. Immediately flush contaminated eyes with gently flowing water. Do not induce vomiting. If vomiting occurs, lean patient forward or place on left side (head-down position, if possible) to maintain an open airway and prevent aspiration. Keep patient quiet and maintain normal body temperature. Obtain medical attention. Beryllium and Related Compounds
Extinguishing media
If material involved in fire: Extinguish fire using agent suitable for type of surrounding fire. (Material itself does not burn or burns with difficulty.) Use water in flooding quantities as fog. Use "alcohol" foam, dry chemical or carbon dioxide. Beryllium compound, NOS
Specific Hazards Arising from the Chemical
Special Hazards of Combustion Products: Toxic beryllium oxide fume may form in fire. (USCG, 1999)
Advice for firefighters
Use fine water spray. In case of fire in the surroundings, use appropriate extinguishing media.
NFPA 704
| HEALTH | 4 | Very short exposure could cause death or major residual injury (e.g. hydrogen cyanide, phosgene, methyl isocyanate, hydrofluoric acid) | |
| FIRE | 0 | Materials that will not burn under typical fire conditions, including intrinsically noncombustible materials such as concrete, stone, and sand. Materials that will not burn in air when exposed to a temperature of 820 °C (1,500 °F) for a period of 5 minutes.(e.g. Carbon tetrachloride) | |
| REACT | 0 | Normally stable, even under fire exposure conditions, and is not reactive with water (e.g. helium,N2) | |
| SPEC. HAZ. |
Personal precautions, protective equipment and emergency procedures
Personal protection: chemical protection suit including self-contained breathing apparatus. Do NOT let this chemical enter the environment. Sweep spilled substance into sealable containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations.
Environmental precautions
Personal protection: chemical protection suit including self-contained breathing apparatus. Do NOT let this chemical enter the environment. Sweep spilled substance into sealable containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations.
Methods and materials for containment and cleaning up
Control of environmental exposure: Prevent further leakage or spillage if safe to do so. Do not let product enter drains.
Precautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Provision to contain effluent from fire extinguishing. Separated from food and feedstuffs. Well closed. Store only in original container. Store in an area without drain or sewer access.Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.
Control parameters
Occupational Exposure limit valuesTLV: (as Be): (inhalable fraction): 0.00005 mg/m3, as TWA; (skin); A1 (confirmed human carcinogen); (SEN).MAK: sensitization of respiratory tract and skin (SAH); carcinogen category: 1
no data available
Exposure controls
Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.
Individual protection measures
Eye/face protectionWear face shield or eye protection in combination with breathing protection if powder.
Protective gloves. Protective clothing.
Use closed system.
no data available
Information on basic physicochemical properties
- Physical statePowder
- Colourwhite
- Odour
Odorless
- Melting point/freezing point
2 428 °C. Atm. press.:101.35 kPa. Remarks:Average melting point during heating, hysteresis was determined (see value for cooling), pressure was not describe in detail but assumed to be close to the standard condition.;2 431 °C. Atm. press.:101.35 kPa. Remarks:Average melting point during cooling, hysteresis was determined (see value for heating), pressure was not describe in detail but assumed to be close to the standard condition.
- Boiling point or initial boiling point and boiling range
3 900 °C. Atm. press.:101.35 kPa. Remarks:The value is a rough approximation.
- Flammability
Not combustible. Gives off irritating or toxic fumes (or gases) in a fire.
- Lower and upper explosion limit/flammability limit
no data available
- Flash point
no data available
- Auto-ignition temperature
no data available
- Decomposition temperature
no data available
- pH
no data available
- Kinematic viscosity
no data available
- Solubility
Insoluble in water; slightly soluble in acid and alkali solutions
- Partition coefficient n-octanol/water
no data available
- Vapour pressure
no data available
- Density and/or relative density3.01
- Relative vapour density3.01
- Particle characteristics
no data available
Reactivity
NIOSH considers beryllium and beryllium compounds (as Be) to be a potential occupational carcinogen.
Upon heating, toxic fumes are formed.
Chemical stability
Stable under recommended storage conditions.
Possibility of hazardous reactions
Not flammable
Conditions to avoid
no data available
Incompatible materials
Can react explosively with magnesium when heated.
Hazardous decomposition products
Special hazards arising from the substance or mixture: Beryllium oxides
Acute toxicity
- Oral: LD50 - rat (female) - > 2 000 mg/kg bw.
- Inhalation: Concentration where an effect was seen in animals - dog (male/female) - ca. 28 μg BeO/l.
- Dermal: no data available
Skin corrosion/irritation
no data available
Serious eye damage/irritation
no data available
Respiratory or skin sensitization
no data available
Germ cell mutagenicity
no data available
Carcinogenicity
There is sufficient evidence in humans for the carcinogenicity of beryllium and beryllium compounds. Beryllium and beryllium compounds cause cancer of the lung. There is sufficient evidence in experimental animals for the carcinogenicity of beryllium and beryllium compounds. Beryllium and beryllium compounds are carcinogenic to humans (Group 1). Beryllium and beryllium compounds
Reproductive toxicity
no data available
STOT-single exposure
The substance is irritating to the eyes and respiratory tract. Inhalation of dust or fume may cause chemical pneumonitis. The effects may be delayed. Medical observation is indicated. Exposure could cause death.
STOT-repeated exposure
Sensitization to the substance, through repeated or prolonged inhalation or skin contact, may result in serious granulomatous lung disease (chronic beryllium disease). This substance is carcinogenic to humans.
Aspiration hazard
A harmful concentration of airborne particles can be reached quickly when dispersed.
Toxicity
- Toxicity to fish: LC50; Species: Pimephales promelas (fathead minnow); Conditions: static; Concentration: 150 ug/L for 96 hr, soft water; 20,000 ug/L for 96 hr, hard water /Beryllium ion
- Toxicity to daphnia and other aquatic invertebrates: no data available
- Toxicity to algae: no data available
- Toxicity to microorganisms: no data available
Persistence and degradability
no data available
Bioaccumulative potential
Bioconcentration of 100 fold can occur under constant exposure. Not significant in spill conditions.
Mobility in soil
no data available
Other adverse effects
no data available
Disposal methods
ProductThe material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.
UN Number
ADR/RID: UN1566 (For reference only, please check.)
IMDG: UN1566 (For reference only, please check.)
IATA: UN1566 (For reference only, please check.)
UN Proper Shipping Name
ADR/RID: BERYLLIUM COMPOUND, N.O.S. (For reference only, please check.)
IMDG: BERYLLIUM COMPOUND, N.O.S. (For reference only, please check.)
IATA: BERYLLIUM COMPOUND, N.O.S. (For reference only, please check.)
Transport hazard class(es)
ADR/RID: 6.1 (For reference only, please check.)
IMDG: 6.1 (For reference only, please check.)
IATA: 6.1 (For reference only, please check.)
Packing group, if applicable
ADR/RID: II (For reference only, please check.)
IMDG: II (For reference only, please check.)
IATA: II (For reference only, please check.)
Environmental hazards
ADR/RID: No
IMDG: No
IATA: No
Special precautions for user
no data available
Transport in bulk according to IMO instruments
no data available
Safety, health and environmental regulations specific for the product in question
European Inventory of Existing Commercial Chemical Substances (EINECS)Abbreviations and acronyms
- CAS: Chemical Abstracts Service
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- IMDG: International Maritime Dangerous Goods
- IATA: International Air Transportation Association
- TWA: Time Weighted Average
- STEL: Short term exposure limit
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- EC50: Effective Concentration 50%
References
- IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
- HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
- IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
- eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
- CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
- ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
- ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
- Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
- ECHA - European Chemicals Agency, website: https://echa.europa.eu/
Other Information
The symptoms of acute pneumonitis following a massive short-term exposure do not become manifest until 3 days.Depending on the degree of exposure, periodic medical examination is suggested.Do NOT take working clothes home.Isolate contaminated clothing by sealing in a bag or other container.
The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.