Metribuzin

Acute toxicity - Category 4, Oral

Hazardous to the aquatic environment, short-term (Acute) - Category Acute 1

Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 1

H225 Highly Flammable liquid and vapour

H302 Harmful if swallowed

H319 Causes serious eye irritation

H331 Toxic if inhaled

H410 Very toxic to aquatic life with long lasting effects

P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P261 Avoid breathing dust/fume/gas/mist/vapours/spray.

P273 Avoid release to the environment.

P280 Wear protective gloves/protective clothing/eye protection/face protection.

P311 Call a POISON CENTER or doctor/physician.

P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P370+P378 In case of fire: Use … for extinction.

P403+P233 Store in a well-ventilated place. Keep container tightly closed.

P403+P235 Store in a well-ventilated place. Keep cool.

P501 Dispose of contents/container to..…

P264 Wash ... thoroughly after handling.

P270 Do not eat, drink or smoke when using this product.

P273 Avoid release to the environment.

P301+P317 IF SWALLOWED: Get medical help.

P330 Rinse mouth.

P391 Collect spillage.

none

P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

no data available

Fresh air, rest.

Rinse and then wash skin with water and soap.

First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.

Rinse mouth. Rest.

Exposure Routes: inhalation, ingestion, skin and/or eye contact Target Organs: central nervous system, thyroid, liver (NIOSH, 2016)

Skin decontamination: Skin contamination should he treated promptly by washing with soap and water. Contamination of the eyes should be treated immediately by prolonged flushing of the eyes with large amounts of clean water. If dermal or ocular irritation persists, medical attention should be, obtained without delay.

Use water spray, powder.

Combustible.

Use water spray, powder.

Do NOT let this chemical enter the environment. Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting. Then store and dispose of according to local regulations.

Do NOT let this chemical enter the environment. Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting. Then store and dispose of according to local regulations.

Collect and arrange disposal. Keep the chemical in suitable and closed containers for disposal. Remove all sources of ignition. Use spark-proof tools and explosion-proof equipment. Adhered or collected material should be promptly disposed of, in accordance with appropriate laws and regulations.

NO open flames. Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Store in an area without drain or sewer access.Estimated shelf life in excess of 2 yr under normal storage conditions.

TLV: 5 mg/m3, as TWA; A4 (not classifiable as a human carcinogen)

no data available

Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.

Wear safety spectacles.

Protective gloves.

Use ventilation (not if powder), local exhaust or breathing protection.

no data available

Decomposes on burning. This produces toxic fumes including nitrogen oxides and sulfur oxides.

no data available

NonflammableA triazine derivative. Amines are chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides.

no data available

This compound is incompatible with the following:None reported (NIOSH, 1997)

When heated to decomposition it emits very toxic fumes of /nitrogen oxides and sulfur oxides/.

no data available

no data available

no data available

no data available

Cancer Classification: Group D Not Classifiable as to Human Carcinogenicity

no data available

Exposure at high levels could cause depression of the central nervous system.

no data available

Evaporation at 20°C is negligible; a harmful concentration of airborne particles can, however, be reached quickly.

In mineral and muck soils, metribuzin metabolism via deamination and thiodealkylation produced: 6-(1,1-dimethylethyl)-3-methylthio-1,2,4-triazin-5- (4H)-one metribuzin; 4-amino-6-(1,1-dimethylethyl)-1,2,4-triazin-3,5-(2H,4H)- dione 3,5-diketo; and 6-(1,1-dimethylethyl)-1,2,4-triazin-3,5-(2H,4H)-dione deaminated diketo. Over a pH range of 4.5 to 6.9 in sandy clay loam, microbial degradation gave (14)CO2 from (14)C ring-labeled metribuzin. It was also observed that metribuzin degradation by soil microoganisms decreased with increasing soil pH.

The bioconcentration factor (BCF) of metribuzin in the Golden ide fish (Leuciscus idus melanotus) was experimentally determined to be 10 in a 3 day static test(1). According to a classification scheme(2) and this BCF value, metribuzin is not expected to bioconcentrate in aquatic organisms(SRC).

The average Koc of metribuzin is 60(1). Parent metribuzin was very mobile in sandy (0.58% OC), sandy loam (0.64% OC), silt loam (1.7% OC), and clay loam (1.3% OC) soils with adsorption(1). Freundlich constant values of 0.25, 0.02, 0.22, and 0.20, respectively desorption Freundlich values were 0.56, 0.14, 0.51, and 0.41, respectively(1). Adsorption Koc were 47, 3, 15, and 17 and desorption Koc values were 106, 24, 33, and 36, respectively(1). The Koc values for metribuzin in Alaskan subarctic agricultural silt loam soils ranges from 34-56(2). Experimental Koc values have been measured for sand (Koc=47; 1% OM, pH 4.3), sandy loam (Koc=3; 1.1% OM, pH 6.6), silt loam (Koc=14; 3% OM, pH 5.9), and clay loam (Koc=17; 2.2% OM, pH 6.4) soils(1). Metribuzin has high affinity for soil organic matter, but is less tightly adsorbed to clay(1). Adsorption of metribuzin decreases as soil pH increases(1). According to a classification scheme(4), these Koc values suggest that metribuzin is expected to have high mobility in soil(SRC).

no data available

The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.

Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.

ADR/RID: UN3077 (For reference only, please check.)

IMDG: UN3077 (For reference only, please check.)

IATA: UN3077 (For reference only, please check.)

ADR/RID: ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S. (For reference only, please check.)

IMDG: ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S. (For reference only, please check.)

IATA: ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S. (For reference only, please check.)

ADR/RID: 9 (For reference only, please check.)

IMDG: 9 (For reference only, please check.)

IATA: 9 (For reference only, please check.)

ADR/RID: III (For reference only, please check.)

IMDG: III (For reference only, please check.)

IATA: III (For reference only, please check.)

ADR/RID: Yes

IMDG: Yes

IATA: Yes

no data available

no data available