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ChemicalBook >> CAS DataBase List >> (2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoic Acid Ethyl Ester Hydrochloride

(2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoic Acid Ethyl Ester Hydrochloride

(2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoic Acid Ethyl Ester Hydrochloride price.
  • $48 - $21666
  • Product name: (2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoic Acid Ethyl Ester Hydrochloride
  • CAS: 149690-12-0
  • MF: C20H26ClNO2
  • MW: 347.88
  • EINECS:695-675-7
  • MDL Number:MFCD27955983
  • Synonyms:(2R,4S)-ethyl 5-([1,1'-biphenyl]-4-yl)-4-aMino-2-Methylpentanoate HCl;LCZ696 Intermediate2;LCZ698;[1,1'-Biphenyl]-4-pentanoic acid, γ-amino-α-methyl-, ethyl ester, hydrochloride (1:1), (αR,γS)-;(2R,4S)-ethyl 5-([1,1'-biphenyl]-4-yl)-4-aMino-2-Methylpentanoate;(2R,4S)-ethyl 5-([1,1'-biphenyl]-4-yl)-4-aMino-2-Methylpentanoate hydrochloride;(2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoic acid ethyl ester hydrochloride;(2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoic acid ethyl ester hydrochloride (1:1)
Price19 Properties Safety Information Description
19 prices
Selected condition：
Brand
  • AccelPharmtech
  • AK Scientific
  • Alichem
  • Ambeed
  • Chemenu
  • Crysdot
  • Labseeker
  • TRC
Package
  • 50mg
  • 1G
  • 5G
  • 10g
  • 25G
  • 100g
  • 1000g
  • 1kg
  • ManufacturerAccelPharmtech
  • Product numberXP1500
  • Product description(2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoicacidethylesterhydrochloride 99%
  • Packaging1G
  • Price$230
  • Updated2021-12-16
  • Buy
  • ManufacturerAccelPharmtech
  • Product numberXP1500
  • Product description(2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoicacidethylesterhydrochloride 99%
  • Packaging5G
  • Price$280
  • Updated2021-12-16
  • Buy
  • ManufacturerAccelPharmtech
  • Product numberXP1500
  • Product description(2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoicacidethylesterhydrochloride 99%
  • Packaging25G
  • Price$710
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number2498DC
  • Product description(2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoicacidethylesterhydrochloride
  • Packaging25g
  • Price$870
  • Updated2021-12-16
  • Buy
  • ManufacturerAlichem
  • Product number149690120
  • Product description(2R,4S)-Ethyl5-([1,1'-biphenyl]-4-yl)-4-amino-2-methylpentanoatehydrochloride
  • Packaging5g
  • Price$157.5
  • Updated2021-12-16
  • Buy
  • ManufacturerAlichem
  • Product number149690120
  • Product description(2R,4S)-Ethyl5-([1,1'-biphenyl]-4-yl)-4-amino-2-methylpentanoatehydrochloride
  • Packaging10g
  • Price$250
  • Updated2021-12-16
  • Buy
  • ManufacturerAlichem
  • Product number149690120
  • Product description(2R,4S)-Ethyl5-([1,1'-biphenyl]-4-yl)-4-amino-2-methylpentanoatehydrochloride
  • Packaging25g
  • Price$490
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA249066
  • Product description(2R,4S)-Ethyl5-([1,1'-biphenyl]-4-yl)-4-amino-2-methylpentanoatehydrochloride 95%
  • Packaging1g
  • Price$48
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA249066
  • Product description(2R,4S)-Ethyl5-([1,1'-biphenyl]-4-yl)-4-amino-2-methylpentanoatehydrochloride 95%
  • Packaging5g
  • Price$135
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA249066
  • Product description(2R,4S)-Ethyl5-([1,1'-biphenyl]-4-yl)-4-amino-2-methylpentanoatehydrochloride 95%
  • Packaging10g
  • Price$241
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA249066
  • Product description(2R,4S)-Ethyl5-([1,1'-biphenyl]-4-yl)-4-amino-2-methylpentanoatehydrochloride 95%
  • Packaging25g
  • Price$404
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA249066
  • Product description(2R,4S)-Ethyl5-([1,1'-biphenyl]-4-yl)-4-amino-2-methylpentanoatehydrochloride 95%
  • Packaging100g
  • Price$1192
  • Updated2021-12-16
  • Buy
  • ManufacturerChemenu
  • Product numberCM244548
  • Product description(2R,4S)-Ethyl5-([1,1''-biphenyl]-4-yl)-4-amino-2-methylpentanoatehydrochloride 95+%
  • Packaging1000g
  • Price$1748
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD12139848
  • Product description(2R,4S)-Ethyl5-([1,1'-biphenyl]-4-yl)-4-amino-2-methylpentanoatehydrochloride 95+%
  • Packaging1g
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD12139848
  • Product description(2R,4S)-Ethyl5-([1,1'-biphenyl]-4-yl)-4-amino-2-methylpentanoatehydrochloride 95+%
  • Packaging5g
  • Price$150
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD12139848
  • Product description(2R,4S)-Ethyl5-([1,1'-biphenyl]-4-yl)-4-amino-2-methylpentanoatehydrochloride 95+%
  • Packaging10g
  • Price$250
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AccelPharmtech XP1500 (2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoicacidethylesterhydrochloride 99% 1G $230 2021-12-16 Buy
AccelPharmtech XP1500 (2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoicacidethylesterhydrochloride 99% 5G $280 2021-12-16 Buy
AccelPharmtech XP1500 (2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoicacidethylesterhydrochloride 99% 25G $710 2021-12-16 Buy
AK Scientific 2498DC (2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoicacidethylesterhydrochloride 25g $870 2021-12-16 Buy
Alichem 149690120 (2R,4S)-Ethyl5-([1,1'-biphenyl]-4-yl)-4-amino-2-methylpentanoatehydrochloride 5g $157.5 2021-12-16 Buy
Alichem 149690120 (2R,4S)-Ethyl5-([1,1'-biphenyl]-4-yl)-4-amino-2-methylpentanoatehydrochloride 10g $250 2021-12-16 Buy
Alichem 149690120 (2R,4S)-Ethyl5-([1,1'-biphenyl]-4-yl)-4-amino-2-methylpentanoatehydrochloride 25g $490 2021-12-16 Buy
Ambeed A249066 (2R,4S)-Ethyl5-([1,1'-biphenyl]-4-yl)-4-amino-2-methylpentanoatehydrochloride 95% 1g $48 2021-12-16 Buy
Ambeed A249066 (2R,4S)-Ethyl5-([1,1'-biphenyl]-4-yl)-4-amino-2-methylpentanoatehydrochloride 95% 5g $135 2021-12-16 Buy
Ambeed A249066 (2R,4S)-Ethyl5-([1,1'-biphenyl]-4-yl)-4-amino-2-methylpentanoatehydrochloride 95% 10g $241 2021-12-16 Buy
Ambeed A249066 (2R,4S)-Ethyl5-([1,1'-biphenyl]-4-yl)-4-amino-2-methylpentanoatehydrochloride 95% 25g $404 2021-12-16 Buy
Ambeed A249066 (2R,4S)-Ethyl5-([1,1'-biphenyl]-4-yl)-4-amino-2-methylpentanoatehydrochloride 95% 100g $1192 2021-12-16 Buy
Chemenu CM244548 (2R,4S)-Ethyl5-([1,1''-biphenyl]-4-yl)-4-amino-2-methylpentanoatehydrochloride 95+% 1000g $1748 2021-12-16 Buy
Crysdot CD12139848 (2R,4S)-Ethyl5-([1,1'-biphenyl]-4-yl)-4-amino-2-methylpentanoatehydrochloride 95+% 1g $50 2021-12-16 Buy
Crysdot CD12139848 (2R,4S)-Ethyl5-([1,1'-biphenyl]-4-yl)-4-amino-2-methylpentanoatehydrochloride 95+% 5g $150 2021-12-16 Buy
Crysdot CD12139848 (2R,4S)-Ethyl5-([1,1'-biphenyl]-4-yl)-4-amino-2-methylpentanoatehydrochloride 95+% 10g $250 2021-12-16 Buy
Next Last

Properties

Melting point :155 - 162°C
storage temp. :under inert gas (nitrogen or Argon) at 2-8°C
solubility :DMSO (Slightly), Methanol (Slightly)
form :Solid
color :White to Off-White
Stability :Hygroscopic
InChI :InChI=1/C20H25NO2.ClH/c1-3-23-20(22)15(2)13-19(21)14-16-9-11-18(12-10-16)17-7-5-4-6-8-17;/h4-12,15,19H,3,13-14,21H2,1-2H3;1H/t15-,19+;/s3
InChIKey :MYJTZLYRAWUSLB-MTPCZXHRNA-N
SMILES :C(C1C=CC(C2C=CC=CC=2)=CC=1)[C@@H](N)C[C@@H](C)C(=O)OCC.Cl |&1:13,16,r|

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

(2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoic Acid Ethyl Ester Hydrochloride is used as a reagent in the synthesis of LCZ696, an angiotensin II receptor and neprilysin receptor dual inhibitor. (2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoic Acid Ethyl Ester Hydrochloride is also used as a reagent in the preparation of novel NEP inhibitor prodrugs for the treatment of hypertension and cardiovascular diseases.

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Related product price

Suppliers and manufacturers

career henan chemical co
(2R,4S)-ethyl 5-([1,1'-biphenyl]-4-yl)-4-aMino-2-Methylpentanoate
$100.00 /1KG
(2R,4S)-ethyl 5-([1,1'-biphenyl]-4-yl)-4-aMino-2-Methylpentanoate CAS:149690-12-0
ChemExpress
Capot Chemical Co.,Ltd.
Shanghai Daken Advanced Materials Co.,Ltd
Beijing Cooperate Pharmaceutical Co.,Ltd
Henan Tianfu Chemical Co.,Ltd.
ATK CHEMICAL COMPANY LIMITED
Jinan Finer Chemical Co., Ltd
Accela ChemBio Inc.
HubeiwidelychemicaltechnologyCo.,Ltd