Streptonigrin
|
- $118 - $700
- Product name: Streptonigrin
- CAS: 3930-19-6
- MF: C25H22N4O8
- MW: 506.46
- EINECS:223-501-8
- MDL Number:MFCD00063401
- Synonyms:rufocromomycin;streptonigrin from streptomyces flocculus;Streptonigrin, Streptomyces flocculus;Bruneomycin, Nigrin;5-Amino-6-(7-amino-5,8-dihydro-6-methoxy-5,8-dioxoquinolin-2-yl)-4-(2-hydroxy-3,4-dimethoxyphenyl)-3-methylpicolinic acid;5-Amino-6-(7-amino-5,8-dihydro-6-methoxy-5,8-dioxo-2-quinolyl)-4-(2-hydroxy-3,4-dimethoxyphenyl)-3-methylpicolinic acid;Abbott Crystalline antibiotic;AO 50165L302
9 prices
Selected condition：
Brand
- Biosynth Carbosynth
- Cayman Chemical
- Sigma-Aldrich
- TRC
- Usbiological
Package
- 1mg
- 2mg
- 2.5mg
- 5mg
- ManufacturerBiosynth Carbosynth
- Product numberFA43266
- Product description5-Amino-6-(7-amino-5,8-dihydro-6-methoxy-5,8-dioxoquinolin-2-yl)-4-(2-hydroxy-3,4-dimethoxyphenyl)-3-methylpicolinic acid
- Packaging1mg
- Price$250
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFA43266
- Product description5-Amino-6-(7-amino-5,8-dihydro-6-methoxy-5,8-dioxoquinolin-2-yl)-4-(2-hydroxy-3,4-dimethoxyphenyl)-3-methylpicolinic acid
- Packaging2mg
- Price$420
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFA43266
- Product description5-Amino-6-(7-amino-5,8-dihydro-6-methoxy-5,8-dioxoquinolin-2-yl)-4-(2-hydroxy-3,4-dimethoxyphenyl)-3-methylpicolinic acid
- Packaging5mg
- Price$700
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number27952
- Product descriptionStreptonigrin
- Packaging1mg
- Price$118
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number27952
- Product descriptionStreptonigrin
- Packaging5mg
- Price$529
- Updated2024-03-01
- Buy
- ManufacturerSigma-Aldrich
- Product numberS1014
- Product descriptionStreptonigrin from Streptomyces flocculus ≥98%
- Packaging1mg
- Price$119
- Updated2024-03-01
- Buy
- ManufacturerSigma-Aldrich
- Product numberS1014
- Product descriptionStreptonigrin from Streptomyces flocculus ≥98%
- Packaging5mg
- Price$432
- Updated2024-03-01
- Buy
- ManufacturerTRC
- Product numberS687555
- Product descriptionStreptonigrin from Streptomyces flocculus
- Packaging2.5mg
- Price$395
- Updated2021-12-16
- Buy
- ManufacturerUsbiological
- Product numberS7975-09
- Product descriptionStreptonigrin
- Packaging1mg
- Price$490
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Biosynth Carbosynth | FA43266 | 5-Amino-6-(7-amino-5,8-dihydro-6-methoxy-5,8-dioxoquinolin-2-yl)-4-(2-hydroxy-3,4-dimethoxyphenyl)-3-methylpicolinic acid | 1mg | $250 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FA43266 | 5-Amino-6-(7-amino-5,8-dihydro-6-methoxy-5,8-dioxoquinolin-2-yl)-4-(2-hydroxy-3,4-dimethoxyphenyl)-3-methylpicolinic acid | 2mg | $420 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FA43266 | 5-Amino-6-(7-amino-5,8-dihydro-6-methoxy-5,8-dioxoquinolin-2-yl)-4-(2-hydroxy-3,4-dimethoxyphenyl)-3-methylpicolinic acid | 5mg | $700 | 2021-12-16 | Buy |
| Cayman Chemical | 27952 | Streptonigrin | 1mg | $118 | 2024-03-01 | Buy |
| Cayman Chemical | 27952 | Streptonigrin | 5mg | $529 | 2024-03-01 | Buy |
| Sigma-Aldrich | S1014 | Streptonigrin from Streptomyces flocculus ≥98% | 1mg | $119 | 2024-03-01 | Buy |
| Sigma-Aldrich | S1014 | Streptonigrin from Streptomyces flocculus ≥98% | 5mg | $432 | 2024-03-01 | Buy |
| TRC | S687555 | Streptonigrin from Streptomyces flocculus | 2.5mg | $395 | 2021-12-16 | Buy |
| Usbiological | S7975-09 | Streptonigrin | 1mg | $490 | 2021-12-16 | Buy |
Properties
Melting point :301-303℃
Boiling point :595.12°C (rough estimate)
Density :1.4130 (rough estimate)
refractive index :1.6000 (estimate)
storage temp. :2-8°C
solubility :Chloroform:Methanol (1:1): 2 mg/ml
form :A solid
pka :6.2-6.4 (1:1 aq dioxane)
Merck :13,8907
BRN :599390
Boiling point :595.12°C (rough estimate)
Density :1.4130 (rough estimate)
refractive index :1.6000 (estimate)
storage temp. :2-8°C
solubility :Chloroform:Methanol (1:1): 2 mg/ml
form :A solid
pka :6.2-6.4 (1:1 aq dioxane)
Merck :13,8907
BRN :599390
Safety Information
| Symbol(GHS): |
|
||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Signal word: | Danger | ||||||||||||||
| Hazard statements: |
|
||||||||||||||
| Precautionary statements: |
|
Description
Streptonigrin is a phenylpyridylquinoline originally isolated from S. flocculus with diverse biological activities. Streptonigrin (2.5-12.5 μM) induces DNA cleavage by calf thymus topoisomerase II in a concentration-dependent manner. It induces phage production in S. typhimurium when used at concentrations ranging from 1 to 10 μg/ml. Streptonigrin (10 μg/ml) inhibits DNA synthesis in and reduces survival of S. typhimurium bacteria. Streptonigrin is bactericidal against E. coli in an iron-dependent manner, an effect that is blocked by the iron chelators deferoxamine and orthophenanthroline. Streptonigrin (40 nM) is cytotoxic to human HT-29 colon carcinoma cells but not to BE colon carcinoma cells in which NAD(P)H:quinone oxidoreductase is not expressed. Streptonigrin (0.001-0.1 μg/ml) inhibits mitosis and induces chromatin breaks in human leukocytes in a concentration-dependent manner. In vivo, streptonigrin (0.05 mg/kg, i.p.) increases the mean survival time in rats infected with Rauscher virus.More related product prices
18085-97-7 CHLOROPHYLL 1-(6-METHYL-PYRIDIN-2-YL)-ETHANONE 3-(2-HYDROXYETHYL)PYRIDINE 5-Methylpyridin-3-amine 1122-71-0 55589-47-4 2,4,6-Collidine 3-Amino-4-methylpyridine ISOAMYLAMINE 2-FORMYL-4-PICOLINE 5-ACETYL-2-METHYLPYRIDINE 4021-08-3 3-Amino-4,6-dimethylpyridine 5-Amino-2-methylpyridine 2-AcetylpyridineRelated product price
- 18085-97-7
$34-790 - CHLOROPHYLL
$27-94.35 - 1-(6-METHYL-PYRIDIN-2-YL)-ETHANONE
$12-1170
