(S)-(3-(3,4-dichlorophenyl)-3-(3-iodopropyl)piperidin-1-yl)(phenyl)methanone synthesis

2synthesis methods

Product Name:(S)-(3-(3,4-dichlorophenyl)-3-(3-iodopropyl)piperidin-1-yl)(phenyl)methanone
CAS Number:188916-67-8
Molecular formula:C21H22Cl2INO
Molecular Weight:502.22

172734-70-2 Synthesis

Yield:-

Steps:

Multi-step reaction with 2 steps
1: 99 percent / DIPEA / CH₂Cl₂ / 2 h / Ambient temperature
2: 98 percent / KI / acetone / 18 h / Heating

References:

Chen, Huai G.;Chung;Goel;Johnson;Kesten;Knobelsdorf;Lee;Rubin [Bioorganic and Medicinal Chemistry Letters,1997,vol. 7,# 5,p. 555 - 560]