ChemicalBook CAS DataBase List 2-Aminonaphthalene-1-sulfonic acid

2-Aminonaphthalene-1-sulfonic acid synthesis

3synthesis methods

Product Name:2-Aminonaphthalene-1-sulfonic acid
CAS Number:81-16-3
Molecular formula:C10H9NO3S
Molecular Weight:223.25

2-Hydroxynaphthalene-1-sulfonic acid is heated with a mixture of ammonia and ammonium sulfite in an autoclave at 150 ℃ and 1 MPa for 30 h. The reaction mixture is added to a slurry of lime, and excess ammonia is driven off. Inorganic calcium salts are filtered off at 80℃, and the filtrate is acidified with hydrochloric acid at 40℃ to precipitate Tobias acid in 95 % yield. Care must be taken throughout the process to avoid desulfonation and formation of 2- naphthylamine.

110-91-8 Synthesis

110-91-8
672 suppliers
$9.00/1g

90-20-0 Synthesis

1-Amino-8-hydroxynaphthalene-3,6-disulphonic acid

90-20-0
230 suppliers
inquiry

112291-51-7
0 suppliers
inquiry

81-16-3
320 suppliers
$21.00/5g

Yield:-

Reaction Conditions:

with sodium carbonate in water

Steps:

1 EXAMPLE 1
EXAMPLE 1 31.9 g of 1-hydroxy-8-aminonaphthalene-3,6-disulphonic acid are dissolved in 400 ml of water under neutral conditions. At 0° to 5° C., 8.8 ml of trifluorotriazine are added, and the pH is maintained at 4.0 to 4.5 by adding 20% strength sodium carbonate solution. After 5 minutes, 9 g of morpholine are added, and the pH is maintained at 7 using 20% strength sodium carbonate solution. After 15 minutes at 10° C., the reaction is complete. The solution thus obtained of the compound of the formula STR9 is further reacted as follows: A diazonium salt suspension obtained by diazotisation of 22.3 g of 2-aminonaphthalene-1-sulphonic acid prepared in the usual manner is added to the reaction product obtained at 0° to 5° C.

References:

Bayer Aktiengesellschaft US5239063, 1993, A

FullText

567-47-5
3 suppliers
inquiry

81-16-3
320 suppliers
$21.00/5g

References

91-59-8
194 suppliers
$54.00/100mg

81-16-3
320 suppliers
$21.00/5g

References

2-Aminonaphthalene-1-sulfonic acid Related Search:

Taurine 1,5-Naphthalenedisulfonic acid 1-DODECANESULFONIC ACID SODIUM SALT Sulfamic acid Ethyl 2-(Chlorosulfonyl)acetate Amlodipine Besylate Folic acid Glycine 4-Amino-benzenesulfonic acid monosodium salt 8-Anilino-1-naphthalenesulfonic acid