ChemicalBook CAS DataBase List 2-(Bromomethyl)pyridine

2-(Bromomethyl)pyridine synthesis

6synthesis methods

Product Name:2-(Bromomethyl)pyridine
CAS Number:55401-97-3
Molecular formula:C6H6BrN
Molecular Weight:172.02

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Yield:55401-97-3 100%

Reaction Conditions:

with potassium carbonate in acetone at 25; for 7 h;

Steps:

L1.2
Step 2; 760 mg (3 mmol) of 2-bromomethylpyridine.HBr and 436 mg (3.15 mmol) of potassium carbonate were degassed under vacuum for 1 hour. 10 ml_ of dry acetone were added and the mixture was stirred under argon for 6 hours at room temperature (about 25 ⁰C). The solvent was removed and the 2-bromomethylpyhdine was extracted with 3 x 10 ml_ of diethyl ether under inert atmosphere. The solvent was removed to afford a pink oil with quantitative yield.

References:

TOTAL PETROCHEMICALS RESEARCH FELUY WO2008/61900, 2008, A1 Location in patent:Page/Page column 8

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586-98-1 Synthesis