2-CHLORO-5-(5-FORMYL-FURAN-2-YL)BENZOIC ACID METHYL ESTER synthesis
- Product Name:2-CHLORO-5-(5-FORMYL-FURAN-2-YL)BENZOIC ACID METHYL ESTER
- CAS Number:355368-67-1
- Molecular formula:C13H9ClO4
- Molecular Weight:264.66
98-01-1
472 suppliers
$22.00/25g
42122-75-8
118 suppliers
$16.00/1g
355368-67-1
13 suppliers
$221.55/100MG
Yield:355368-67-1 67.7%
Reaction Conditions:
Stage #1: methyl 2-chloro-5-aminobenzoatewith hydrogenchloride;sodium nitrite in water at 0;
Stage #2: furfuralwith copper dichloride in water at 0 - 20;
References:
He, Lingyan;Zhang, Liang;Liu, Xiaofeng;Li, Xianghua;Zheng, Mingyue;Li, HongLin;Yu, Kunqian;Chen, Kaixian;Shen, Xu;Jiang, Hualiang;Liu, Hong [Journal of Medicinal Chemistry,2009,vol. 52,# 8,p. 2465 - 2481] Location in patent:experimental part