ChemicalBook CAS DataBase List 5-Aminolevulinic acid methyl ester hydrochloride

5-Aminolevulinic acid methyl ester hydrochloride synthesis

5synthesis methods

Product Name:5-Aminolevulinic acid methyl ester hydrochloride
CAS Number:79416-27-6
Molecular formula:C6H12ClNO3
Molecular Weight:181.62

5451-09-2 Synthesis

5451-09-2
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$16.80/1G

5-Aminolevulinic acid methyl ester hydrochloride

79416-27-6
199 suppliers
$19.00/100mg

Yield:-

Reaction Conditions:

with hydrogenchloride in methanol

Steps:

1 Preparation of Methyl 5-aminolevulinate Hydrochloride
EXAMPLE 1 Preparation of Methyl 5-aminolevulinate Hydrochloride To a 500 ml glass reactor containing 200 ml methanol, was added 1 g 5-amino-levulinic acid hydrochloride and 1 drop conc. HCl. The reaction mixture was then stirred overnight at 60° C. The progress of the esterification was followed by ¹ H-NMR. Excess methanol was removed by distillation, and the product further dried under vacuum at 30-40° C., giving methyl 5-aminolevulinate hydrochloride. The structure was confirmed by ¹ H-NMR in DMSO-d₆.

References:

PhotoCure AS US6034267, 2000, A

FullText

67-56-1 Synthesis