ChemicalBook CAS DataBase List Acetamide

Acetamide synthesis

12synthesis methods

Product Name:Acetamide
CAS Number:60-35-5
Molecular formula:C2H5NO
Molecular Weight:59.07

79-20-9 Synthesis

79-20-9
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60-35-5
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$13.00/25g

Yield:60-35-5 98%

Reaction Conditions:

with ammonium hydroxide at 36; under 525.053 Torr; for 8 h;Temperature;Pressure;

Steps:

3

3 mol of methyl acetate solution, 5 mol of aqueous ammonia was added to the reaction vessel, the temperature of the solution was raised to 36 ° C, and the stirring Speed 150rpm, stirring time 110min, placed 8h, 70kPa vacuum distillation so that the solution volume reduced by half, reduce the solution temperature Degrees to 10 ° C, Precipitation of crystals, followed by the mass fraction of 86% ether solution washing, the mass fraction of 95% methanol solution washing, anhydrous sodium sulfate dehydrating agent dehydration, the product of acetamide 173.46g, the yield of 98%.

References:

CN106631870,2017,A Location in patent:Paragraph 0014; 0015

75-05-8 Synthesis