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AKOS B007547 synthesis

2synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1: 59 percent / H2SO4 / 24 h / Heating
2: 85 percent / H2 / 5 percent Pd/C / ethanol / 4 h / 2585.74 Torr

References:

Skibo, Edward B.;Huang, Xiaofen;Martinez, Rogelio;Lemus, Robert H.;Craigo, William A.;Dorr, Robert T. [Journal of Medicinal Chemistry,2002,vol. 45,# 25,p. 5543 - 5555]