ChemicalBook CAS DataBase List Dimethyl 5-nitroisophthalate

Dimethyl 5-nitroisophthalate synthesis

5synthesis methods

Product Name:Dimethyl 5-nitroisophthalate
CAS Number:13290-96-5
Molecular formula:C10H9NO6
Molecular Weight:239.18

67-56-1 Synthesis

67-56-1
734 suppliers
$9.00/25ml

618-88-2 Synthesis

618-88-2
481 suppliers
$13.00/25g

13290-96-5
387 suppliers
$8.00/25g

Yield:13290-96-5 98%

Reaction Conditions:

with sulfuric acid for 3 h;Inert atmosphere;Reflux;

Steps:

1 Example 1. Synthesis of 5 - Nitroisophthalic Acid Dimethyl Ester

In a 100 mL round bottom flask equipped with a condenser, an electric stirrer and a thermometer5.0 g of 5-nitroisophthalic acid,Add 33.3ml of methanol, in the case of N2, stirring at room temperature, 3min or so, the solid completely dissolved, the solution colorless and clear and transparent, and then slowly add 1.0ml concentrated sulfuric acid, heating reflux, about 3h white solid precipitation, TLC (CH2Cl2: CH3OH = 10: 1), cooled, crystallized, filtered, washed with a small amount of water and the filter cake was dried to give dimethyl 5-nitroisophthalate. The yield was 98%.

References:

CN105254521,2016,A Location in patent:Paragraph 0025

618-88-2 Synthesis

618-88-2
481 suppliers
$13.00/25g

13290-96-5
387 suppliers
$8.00/25g

References

99-27-4 Synthesis