Dipropyl sebacate synthesis

Yield:15419-91-7 69%

Reaction Conditions:

with 6H₂O*Na₃[AlMo₆O₁₈(OH)6] at 140;Green chemistry;

Steps:

Esterification

General procedure: The esterification reaction was carried out in a reaction tube with oil bath pot stirred magnetically. The esterification was carried at different temperatures by varying the catalyst amount (0.5-1.5 mol.%), molar ratio (2:1-6:1), and reaction time (4-12 h). Taking the preparation of dipropyl succinate as an example, 1.18 g of succinic acid,2.4 g of propanol, and 0.1170 g of [AlMo6] were added to the reaction test tube and then stirred at 100° C for 8 h. After esterification, the catalysts were separated from reaction liquid by gravity separation method and subjected to subsequent extraction and concentration to obtain purified dipropyl succinate. Other diester products were obtained by the same preparation method.

References:

Lu, Deli;Xu, Yumeng;Chen, Zhe;Han, Sheng [Research on Chemical Intermediates,2022,vol. 48,# 1,p. 321 - 337]