ethyl 2-cyano-3-ethoxycrotonate synthesis
1synthesis methods
- Product Name:ethyl 2-cyano-3-ethoxycrotonate
- CAS Number:35260-93-6
- Molecular formula:C9H13NO3
- Molecular Weight:183.2
Yield: 79.5%
Reaction Conditions:
with acetic acid at 110 - 120; for 18 h;Inert atmosphere;Large scale;
References:
Fandrick, Daniel R.;Sanyal, Sanjit;Kaloko, Joseph;Mulder, Jason A.;Wang, Yuwen;Wu, Ling;Lee, Heewon;Roschangar, Frank;Hoffmann, Matthias;Senanayake, Chris H. [Organic Letters,2015,vol. 17,# 12,p. 2964 - 2967] Location in patent:supporting information