ChemicalBook CAS DataBase List Isothiazolinones

Isothiazolinones synthesis

6synthesis methods

Product Name:Isothiazolinones
CAS Number:26172-55-4
Molecular formula:C4H4ClNOS
Molecular Weight:149.6

999-72-4
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$25.00/250mg

26172-55-4
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$15.00/1g

Yield:26172-55-4 95%

Reaction Conditions:

with chlorine;potassium iodide in ethyl acetate at 40 - 55; for 0.25 h;

Steps:

2 Example 2: Preparation of CMIT / MIT

N, N'-dimethyl-3,3'-dithiodipropionamide, ethyl acetate and potassium iodide were continuously fed into the preheating system at a ratio of 100: 500: 0.2,Preheat the mixture to 40 ~ 45 ° C.The solid-liquid mixture is uniformly mixed into a slurry through a static mixer, and then sent to a pipeline reactor for reaction. The pipeline reactor is fed with chlorine gas at multiple points and controlled by a temperature control system.The reaction temperature is 50 to 55 ° C, and the residence time is 15 minutes.After the reaction liquid from the pipeline reactor is separated by gas and liquid, it enters the post-processing system.After the post-treatment process, a 14% CMIT / MIT aqueous solution was obtained, the chlorine ratio was 3: 1, and the yield was 95%.During the process, all hydrogen chloride gas enters the hydrogen chloride absorption system to produce by-product hydrochloric acid.

References:

CN110483438,2019,A Location in patent:Paragraph 0018

999-72-4
91 suppliers
$25.00/250mg

26172-55-4
365 suppliers
$15.00/1g

2682-20-4 Synthesis