ChemicalBook CAS DataBase List o-Toluidine

o-Toluidine synthesis

14synthesis methods

Product Name:o-Toluidine
CAS Number:95-53-4
Molecular formula:C7H9N
Molecular Weight:107.15

The production of O-toluidine is based on the catalytic hydrogenation of O-nitrotoluene or the amination of toluene with methylhydroxylamine in the presence of aluminum trichloride (Windholz 1983). It is available as a technical grade with a minimum of 99.5% purity containing m-toluidine (0.4% maximum) and/or ptoluidine (0.1% maximum) as impurities (Anon. 1978). The stabilized technical grade may also contain less than 0.5% of unidentified stabilizing agents to prevent darkening.

31656-92-5
12 suppliers
$229.00/10ml

95-53-4
429 suppliers
$10.00/1g

Yield:95-53-4 93%

Reaction Conditions:

with 2-(bis(4-methoxyphenyl)phosphanyl)-5-methylbenzenesulfonamide in tetrahydrofuran at 30; for 3 h;Inert atmosphere;Staudinger Azide Reduction;

Steps:

General Procedure A (for the substrates 1a-1m)

General procedure: Under a N2 atmosphere, the correspondingorganic azide (1.00 mmol, 1.0 equiv) was dissolved in anhydrous tetrahydrofuran(10 mL), followed by the addition of 2c (1.10 mmol, 1.1 equiv). The mixture was stirredat 30 C for 3 h. Upon completion, the mixture was concentrated in vacuo and the crudeproduct was purified by flash column chromatography.

References:

Li, Xingzhuo;Wang, Zhenguo;Luo, Wenjun;Wang, Zixu;Yin, Keshu;Li, Le [Molecules,2022,vol. 27,# 17,art. no. 5707]

16419-60-6 Synthesis

16419-60-6
368 suppliers
$9.00/1g

95-53-4
429 suppliers
$10.00/1g

References

95-46-5 Synthesis

95-46-5
293 suppliers
$10.00/10g

95-53-4
429 suppliers
$10.00/1g

References

88-72-2
246 suppliers
$15.00/5g

95-53-4
429 suppliers
$10.00/1g

References

615-37-2 Synthesis

615-37-2
292 suppliers
$5.00/5g

95-53-4
429 suppliers
$10.00/1g

References

o-Toluidine Related Search:

N,N-Dimethylaniline N,N-Dimethyl-1,4-phenylenediamine N-Methylaniline Glycine N,N-Dimethyl-p-toluidine Methyl acetate Paraquat dichloride Methylparaben Betaine 4-Chloro-2-methylaniline