ChemicalBook CAS DataBase List (R)-1-(Naphthalen-1-yl)ethanol

(R)-1-(Naphthalen-1-yl)ethanol synthesis

11synthesis methods

Product Name:(R)-1-(Naphthalen-1-yl)ethanol
CAS Number:42177-25-3
Molecular formula:C12H12O
Molecular Weight:172.22

57605-95-5 Synthesis

57605-95-5
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42177-25-3
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$86.00/250mg

Yield: 88%

Reaction Conditions:

with Candida parapsilosis MTCC 1965 in aq. phosphate buffer; pH=7 at 30; for 12 h;Microbiological reaction;stereoselective reaction;Temperature;Time;pH-value;Solvent;

Steps:

Synthesis of (R)-1-(1-naphthyl) ethanol using whole cells of Candida parapsilosis
Reaction mixture (20 mL) was prepared by suspending 4 g (wet weight) of cellpellets in phosphate buffer (pH 7, 50 mM). The final substrate concentrationwas 2 mM racemic alcohol in the reaction mixture. This was incubated at 30 C(200 rpm) for 12 h. Ethyl acetate extraction was carried out and the organiclayer was dried with anhydrous sodium sulphate and evaporated undervacuum. Product obtained was solubiliszd in IPA and analyzed by Chiral HPLC.

References:

Amrutkar, Suyog Madhav;Banoth, Linga;Banerjee, Uttam Chand [Tetrahedron Letters,2013,vol. 54,# 25,p. 3274 - 3277] Location in patent:supporting information

57605-95-5 Synthesis

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941-98-0 Synthesis