Pharmaceutical intermediates are the drugs used as raw materials for the production of bulk drugs, or they can refer to a material produced during synthesis of an API that must undergo further molecular change or processing before it becomes an API. Drug intermediates are hygienically formulated using high grade raw materials and they are used in the pharmaceutical and cosmetic industry.
What is (E)-1-Ethoxyethene-2-ylboronic acid pinacol ester?
(E)-1-Ethoxyethene-2-ylboronic acid pinacol ester is a boronic ester used in Suzuki-Miyaura cross-coupling reactions. Thus, it can be used to synthesize azaindole and diazaindoles from chloroamino-N-h
Jan 9，2020 Pharmaceutical intermediates
What is 2,4,6-triphenylpyrylium fluoroborate?
2,4,6-Triphenylpyrylium fluoroborate can be used as photocatalyst to catalyze the photoinduced electron-transfer (PET)-promoted reaction.
Jan 7，2020 Pharmaceutical intermediates
2,4,5-Trichloropyrimidine-Application
2,4,5-Trichloropyrimidine is used in the synthesis of potent and selective anaplastic lymphoma kinase (ALK-5) inhibitors, used as an anti-tumor treatment. It is also used in the synthesis of EGFR inhi
Dec 30，2019 Pharmaceutical intermediates
the synthesis of 2,6-Pyridinedicarbonitrile
2,6-Pyridinedicarbonitrile is a heterocyclic dinitrile, which may be used to synthesize bis-tetrazoles and pyridine-based tridentate ligand 2,6-bis(α-aminoisopropyl)pyridine.
Dec 27，2019 Pharmaceutical intermediates
Synthesis of 2-Deoxy-2,2-difluoro-D-erythro-pentofuranos-1-ulose-3,5-dibenzoate
2-Deoxy-2,2-difluoro-D-erythro-pentofuranos-1-ulose-3,5-dibenzoate (CAS: 122111-01-7) is a compound useful in organic synthesis and it is the key intermediate of gemcitabine.
Dec 27，2019 Pharmaceutical intermediates
Tautomerism characteristics of 4-pyrimidone
Pyrimidone is the name given to either of two heterocyclic compounds with the formula C4H4N2O: 2-pyrimidone and 4-pyrimidone.
Dec 27，2019 Pharmaceutical intermediates
Applications of 3-Fluoro-4-(4-methylpiperazin-1-yl)aniline
3-Fluoro-4-(4-methylpiperazin-1-yl)aniline is an important organic building block to synthetize substituted aniline products.
Dec 26，2019 Pharmaceutical intermediates
The role of 5-chloro-2-phenoxyphenylacetic acid as asenapine intermediate
5-chloro-2-phenoxyphenylacetic acid is the intermediate of asenapine synthesis, and Marco talked about the synthesis routes starting from 5-chloro-2-phenoxyphenylacetic acid as shown in scheme 1[2].
Dec 23，2019 Pharmaceutical intermediates
1-Methyl-aminomethyl naphthalene-Application
1-Methyl-aminomethyl naphthalene has been used as reagent for the determination of isocyanates in air by UV or fluorescence detection.
Dec 19，2019 Pharmaceutical intermediates
The application of methyl 5-chloro-6-methylpyrazine-2-carboxylate in physiology
The N-methyl-d-aspartate (NMDA) receptor is arguably an important signaling mechanism in the human brain and NMDA receptors play a critical role in regulating the strength of synapses, that is, in reg
Dec 18，2019 Pharmaceutical intermediates