Pharmaceutical intermediates are the drugs used as raw materials for the production of bulk drugs, or they can refer to a material produced during synthesis of an API that must undergo further molecular change or processing before it becomes an API. Drug intermediates are hygienically formulated using high grade raw materials and they are used in the pharmaceutical and cosmetic industry.
Pharmaceutical Intermediate - 5-Fluoro-2-oxindole
5- fluorindole-2 - ketone is a useful intermediate of sunitinib and its derivatives. Sunitinib is the first of a new class of drugs that selectively target multiple receptor tyrosine kinases.
Feb 22，2022 Pharmaceutical intermediates
The synthesis and introduction of 1,4-Butanediol
1,4-Butanediol is an organic compound with molecular formula of c4h10o2 and molecular weight of 90.12. The appearance is colorless or light yellow oily liquid.
Feb 15，2022 Pharmaceutical intermediates
2-Pyrazoline - Synthesis, Properties, Reactivity, Oxidation etc.
The parent pyrazoline is an oil with a faint amine-like odor soluble in organic solvents; it has a bp of 144°C volatile with steam, a density of 1.02 g/cm3 , and is miscible with water and alcohol.
Jan 29，2022 Pharmaceutical intermediates
Pyrazole - Properties, Synthesis, Reactions etc.
Pyrazole is a colorless crystalline solid with a pyridine-like odor and weak base, with a pKb of 11.5. It is partially soluble in water with an mp of 70°C and a bp of 188°C. In concentrated solution
Jan 29，2022 Pharmaceutical intermediates
Synthesis of Benzo[c]thiophene
Benzo[c]thiophene, also known as isobenzothiophene, is a bicyclic heteroaromatic sulfur heterocycle, constituted by fusion of benzene with the“c” site (3,4-positions) of the thiophene ring. It is less
Jan 28，2022 Pharmaceutical intermediates
The role of 1,2,4-triazole
Triazole is an aromatic five membered heterocyclic compound. Its unique structure is conducive to the formation of a variety of non covalent bonds and is easy to promote the binding of proteins, enzym
Jan 27，2022 Pharmaceutical intermediates
4,5-Dihydroisoxazole
4,5-Dihydroisoxazoles having a proton at the C3-position easily undergo isomerization under the influence of a base to generate β-hydroxynitriles.
Jan 21，2022 Pharmaceutical intermediates
The bile acids——Tauroursodeoxycholic acid
Tauroursodeoxycholic acid is a bile acid taurine conjugate derived from ursoodeoxycholic acid. It has a role as a human metabolite, an anti-inflammatory agent, a neuroprotective agent, an apoptosis in
Dec 31，2021 Pharmaceutical intermediates
Benzalkonium chloride
Benzalkonium chloride (BACs) is a common bactericidal disinfectant, its main component is dodecyl dimethyl benzyl ammonium chloride (DDBAC). BACs are the most common active ingredients in disinfectant
Nov 9，2021 Pharmaceutical intermediates
Toxicity of 4-Aminopyridine
Avitrol is the most popular avicide that is registered at the US Environmental Protection Agency for the control of certain pest birds that feed on cattle feedlots, field corn, wheat, sorghum, sunflow
Nov 5，2021 Pharmaceutical intermediates