How to prepare Bis(pinacolato)diboron?
Bis(pinacolato)diboron is a covalent compound containing two boron atoms and two pinacolato ligands. The pinacol groups are sometimes abbreviated as "pin", so the structure is sometimes represented as
Dec 24，2019 Organic Solvents
Loratinib – a cyclic ether used in the treatment of Non-small Cell Lung Cancer
Lorlatinib is a small molecule inhibitor of ALK and ROS1 kinase developed by Pfizer for the treatment of ALK-positive non-small cell lung cancer. It has a role as an antineoplastic agent and an EC 2.7
Dec 24，2019 Inhibitors
Aconine – an alkaloid from Aconitum species
Aconine is an alkaloid originally isolated from Aconitum species and active metabolite of aconitine [1]. It inhibits osteoclast differentiation of RANKL-stimulated RAW 264.7 cells and bone resorption
Dec 24，2019 Chinese Herbs
Tomatidine – a natural small molecule from tomato plants
Tomatidine is the aglycone derivative of tomatine. Tomatidine belongs to the chemical family known as Spirosolanes and Derivatives. These are steroidal alkaloids whose structure contains a spirosolane
Dec 24，2019 Natural Products
What can bis(trimethoxysilylpropyl)amine be used industrially?
Bis[3-(trimethoxysilyl)propyl]amine (BTMSPA) is a bis-amino silane which can be used as a water based coupling agent that promotes the adhesion between different materials to form a hybrid material. T
Dec 23，2019 Chemical Reagents
The role of 5-chloro-2-phenoxyphenylacetic acid as asenapine intermediate
5-chloro-2-phenoxyphenylacetic acid is the intermediate of asenapine synthesis, and Marco talked about the synthesis routes starting from 5-chloro-2-phenoxyphenylacetic acid as shown in scheme 1[2].
Dec 23，2019 Pharmaceutical intermediates
Intermediate role of 4,4-piperidinediol hydrochloride in organic synthesis
4-piperidone hydrochloride, monohydrate, also known as azinanone hydrochloride, is a derivative of piperidine used as an intermediate in manufacturing pharmaceutical drugs and chemicals [1].
Dec 23，2019 Organic Chemistry
Chrysosplenetin B – an O-methylated flavonol
Chrysosplenetin B is a tetramethoxyflavone that is the 3,6,7,3'-tetramethyl ether derivative of quercetagetin. It has a role as an antiviral agent and a plant metabolite.
Dec 23，2019 Natural Products
Tomatine – a glycoalkaloid in tomato plants
Tomatine is a glycoalkaloid, found in the stems and leaves of tomato plants, and in the fruits at much lower concentrations. It has fungicidal, antimicrobial, and insecticidal properties.
Dec 23，2019 Natural Products
Calycosin – an O-methylated isoflavone
Calycosin is an O-methylated isoflavone. It can be isolated from Astragalus membranaceus Bge. var. mongholicus and Trifolium pratense L.
Dec 23，2019 Natural Products