Identification | Back Directory | [Name]
l-Ethambutol | [CAS]
10054-05-4 | [Synonyms]
l-Ethambutol Ethambutol, (R,R)- Ethambutol EP Impurity C Ethambutol hydrochloride impurity III l-2,2'-(Ethylenediimino)bis(1-butanol) 1-Butanol, 2,2'-(ethylenediimino)di-, (-)- (8CI) 1-Butanol, 2,2'-(1,2-ethanediyldiimino)bis-, (2R,2'R)- 1-Butanol, 2,2'-(1,2-ethanediyldiimino)bis-, [R-(R*,R*)]- 1-Butanol,2,2'-(1,2-ethanediyldiimino)bis-, (2R,2'R)- (9CI) | [Molecular Formula]
C10H24N2O2 | [MOL File]
10054-05-4.mol | [Molecular Weight]
204.31 |
Chemical Properties | Back Directory | [Melting point ]
88-89 °C(Solv: tetrahydrofuran (109-99-9); ethyl acetate (141-78-6)) | [Boiling point ]
345.3±22.0 °C(Predicted) | [density ]
0.987±0.06 g/cm3(Predicted) | [pka]
14.43±0.10(Predicted) |
Hazard Information | Back Directory | [Uses]
(R,R)-Ethambutol is an antituberculosis compound with tuberculosis inhibitory activity. (R,R)-Ethambutol is often used in combination with other antituberculosis compounds to enhance the efficacy. (R,R)-Ethambutol can also be used to inhibit Mycobacterium avium complex infection and Mycobacterium kansasii infection[1]. | [Definition]
ChEBI: (2R)-2-[2-[[(2R)-1-hydroxybutan-2-yl]amino]ethylamino]-1-butanol is an amino alcohol. | [References]
[1] Clofazimine for the Treatment of Mycobacterium kansasii DOI:10.1128/AAC.00248-18 |
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