ChemicalBook--->CAS DataBase List--->10054-05-4

10054-05-4

10054-05-4 Structure

10054-05-4 Structure
IdentificationBack Directory
[Name]

l-Ethambutol
[CAS]

10054-05-4
[Synonyms]

l-Ethambutol
Ethambutol, (R,R)-
Ethambutol EP Impurity C
Ethambutol hydrochloride impurity III
l-2,2'-(Ethylenediimino)bis(1-butanol)
1-Butanol, 2,2'-(ethylenediimino)di-, (-)- (8CI)
1-Butanol, 2,2'-(1,2-ethanediyldiimino)bis-, (2R,2'R)-
1-Butanol, 2,2'-(1,2-ethanediyldiimino)bis-, [R-(R*,R*)]-
1-Butanol,2,2'-(1,2-ethanediyldiimino)bis-, (2R,2'R)- (9CI)
[Molecular Formula]

C10H24N2O2
[MOL File]

10054-05-4.mol
[Molecular Weight]

204.31
Chemical PropertiesBack Directory
[Melting point ]

88-89 °C(Solv: tetrahydrofuran (109-99-9); ethyl acetate (141-78-6))
[Boiling point ]

345.3±22.0 °C(Predicted)
[density ]

0.987±0.06 g/cm3(Predicted)
[pka]

14.43±0.10(Predicted)
Hazard InformationBack Directory
[Uses]

(R,R)-Ethambutol is an antituberculosis compound with tuberculosis inhibitory activity. (R,R)-Ethambutol is often used in combination with other antituberculosis compounds to enhance the efficacy. (R,R)-Ethambutol can also be used to inhibit Mycobacterium avium complex infection and Mycobacterium kansasii infection[1].
[Definition]

ChEBI: (2R)-2-[2-[[(2R)-1-hydroxybutan-2-yl]amino]ethylamino]-1-butanol is an amino alcohol.
[References]

[1] Clofazimine for the Treatment of Mycobacterium kansasii DOI:10.1128/AAC.00248-18
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