| Identification | Back Directory | [Name]
DIPERODON | [CAS]
101-08-6 | [Synonyms]
Diothane
DIPERODON
Diperodone
YUGZHQHSNYIFLG-UHFFFAOYSA-N
(piperidinomethyl)ethylene dicarbanilate
3-Piperidino-1,2-propanediol bis(N-phenylcarbamate)
Bis(N-phenylcarbamic acid) 3-piperidino-1,2-propanediyl
Bis(N-phenylcarbamic acid)3-piperidino-1,2-propanediyl ester
1,2-PROPANEDIOL,3-(1-PIPERIDINYL)-,BIS(PHENYLCARBAMATE)(ESTER)
1,2-Propanediol, 3-(1-piperidinyl)-, 1,2-bis(N-phenylcarbamate) | [EINECS(EC#)]
202-913-1 | [Molecular Formula]
C22H27N3O4 | [MDL Number]
MFCD00864459 | [MOL File]
101-08-6.mol | [Molecular Weight]
397.47 |
| Chemical Properties | Back Directory | [Boiling point ]
520.91°C (rough estimate) | [density ]
1.2228 (rough estimate) | [refractive index ]
1.6500 (estimate) | [pka]
pKa 8.44(H2O) (Occasionally) |
| Hazard Information | Back Directory | [Originator]
Diothane Hydrochloride,HMR | [Definition]
ChEBI: N-phenylcarbamic acid [2-[anilino(oxo)methoxy]-3-(1-piperidinyl)propyl] ester is a carbamate ester. | [Manufacturing Process]
15.0 g phenylisocyanate in 100 ml of anhydrous ether are added to 10 g of N-
(1,2-dihydroxypropyl)-piperidine (prepared from glycide and piperidine) and
the solution boiled for two hours, after which it is cooled and saturated with
dry hydrogen chloride gas. The ether layer is then decanted off and the
remaining insoluble product is dissolved in a hot mixture of acetone and ethyl
acetate which on cooling precipitates white crystals of the hydrochloride of the
ester of 1,2-propanediol, 3-(1-piperidinyl)-, bis(phenylcarbamate); MP 197°-
198°C. A base form may be prepared by adding an equivalent of triethyl
amine. | [Therapeutic Function]
1,2-Propanediol, 3-(1-piperidinyl)-, bis(phenylcarbamate)
(ester), hydrochloride |
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