| Identification | Back Directory | [Name]
Antroquinonol | [CAS]
1010081-09-0 | [Synonyms]
Antroquinonol
2-Cyclohexen-1-one, 4-hydroxy-2,3-dimethoxy-6-methyl-5-[(2E,6E)-3,7,11-trimethyl-2,6,10-dodecatrien-1-yl]-, (4R,5R,6R)- | [Molecular Formula]
C24H38O4 | [MOL File]
1010081-09-0.mol | [Molecular Weight]
390.56 |
| Chemical Properties | Back Directory | [Boiling point ]
539.3±50.0 °C(Predicted) | [density ]
1.01±0.1 g/cm3(Predicted) | [form ]
Solid | [pka]
12.39±0.70(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Definition]
ChEBI: Antroquinonol is an enone that is cyclohex-2-en-1-one substituted by a hydroxy group at position 4, methoxy groups at positions 2 and 3, a methyl group at position 6 and a (2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-yl group at position 5 (the 4R,5R,6R stereoisomer). It is isolated from the solid-state fermented mycelium of the fungus Antrodia camphorata and has been found to exhibit potent cytotoxicity against a number of human cancer cell lines. However, a synthesis-enabled biological re-examination published in 2016, revealed minimal in vitro and in vivo antitumour activity in preclinical models. It has a role as an antineoplastic agent and a fungal metabolite. It is an enone, a secondary alcohol and an enol ether. |
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