ChemicalBook--->CAS DataBase List--->101403-24-1

101403-24-1

101403-24-1 Structure

101403-24-1 Structure
IdentificationBack Directory
[Name]

(S)-1,2,3,4-tetrahydro-5-methoxy-N-propyl-2-Naphthalenamine(Rotigotine)
[CAS]

101403-24-1
[Synonyms]

Rotigotine InterMediate
(S)-5-Methoxy-N-propyl-1,2,3,4-tetrahydronaphthalen-2-aMine
(S)-1,2,3,4-Tetrahydro-5-methoxy-N-propyl-2-naphthalenamine
(2S)-5-methoxy-N-propyl-1,2,3,4-tetrahydronaphthalen-2-amine
2-NaphthalenaMine, 1,2,3,4-tetrahydro-5-Methoxy-N-propyl-, (S)-
(S)-1,2,3,4-Tetrahydro-5-methoxy-N-propyl-2-naphthalenamine HCl
2-Naphthalenamine, 1,2,3,4-tetrahydro-5-methoxy-N-propyl-, (2S)-
(S)-1,2,3,4-tetrahydro-5-methoxy-N-propyl-2-Naphthalenamine(Rotigotine)
[Molecular Formula]

C14H21NO
[MDL Number]

MFCD09955349
[MOL File]

101403-24-1.mol
[Molecular Weight]

219.32
Chemical PropertiesBack Directory
[Boiling point ]

346.1±42.0 °C(Predicted)
[density ]

1.01±0.1 g/cm3(Predicted)
[solubility ]

soluble in Methanol
[pka]

10.26±0.20(Predicted)
Hazard InformationBack Directory
[Uses]

(S)-1,2,3,4-Tetrahydro-5-methoxy-N-propyl-2-naphthalenamine is an intermediate in the production of antipsychotic agents and antiparkinson medications. (S)-1,2,3,4-Tetrahydro-5-methoxy-N-propyl-2-naphthalenamine Di-p-toluoyl-L-tartaric Acid Salt is an impurity in the synthesis of ent-Rotigotine (R700705), which is a non-ergot dopamine agonist drug and is indicated for the treatment of Parkinson’s disease.
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