| Identification | Back Directory | [Name]
8-CHLOROQUINAZOLIN-4(1H)-ONE | [CAS]
101494-95-5 | [Synonyms]
8-chloroquinazolin-4-ol
8-CHLOROQUINAZOLIN-4(1H)-ONE
8-chloroquinazolin-4(3H)-one
8-Chloro-3H-quinazolin-4-one
4(3H)-Quinazolinone, 8-chloro-
8-chloro-3,4-dihydroquinazolin-4-one | [Molecular Formula]
C8H5ClN2O | [MDL Number]
MFCD09954861 | [MOL File]
101494-95-5.mol | [Molecular Weight]
180.59 |
| Chemical Properties | Back Directory | [Melting point ]
302℃ | [Boiling point ]
327.4±44.0 °C(Predicted) | [density ]
1.50±0.1 g/cm3 (20 ºC 760 Torr) | [storage temp. ]
Sealed in dry,Room Temperature | [form ]
solid | [pka]
0.05±0.20(Predicted) | [color ]
Off-white |
| Hazard Information | Back Directory | [Uses]
8-Chloroquinazolin-4-ol (Compd 18) is a PARP-1 enzyme inhibitor, with an IC50 of 5.65 μM[1]. | [References]
[1] Shridhar S Kulkarni, et al. Synthesis and SAR optimization of quinazolin-4(3H)-ones as poly(ADP-ribose)polymerase-1 inhibitors. Eur J Med Chem. 2012 Apr:50:264-73. DOI:10.1016/j.ejmech.2012.02.001 |
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NovoChemy Ltd.
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021-31261262/ 49 (0)17662837245 |
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www.novochemy.com |
| Company Name: |
SynAsst Chemical.
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021-60343070 |
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www.chemicalbook.com/ShowSupplierProductsList15848/0.htm |
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