| Identification | Back Directory | [Name]
ADENOSINE 3':5'-CYCLIC MONOPHOSPHATE TRIS SALT | [CAS]
102029-77-6 | [Synonyms]
CAMP TRIS SALT
cAMP, cyclic AMP
CYCLIC AMP TRIS SALT
-cyclicMonophosphateTrisSalt
ADENOSINE 3':5'-CYCLIC MONOPHOSPHATE TRIS
ADENOSINE 3':5'-CYCLIC MONOPHOSPHATE TRIS SALT | [Molecular Formula]
C14H23N6O9P | [MDL Number]
MFCD00058346 | [MOL File]
102029-77-6.mol | [Molecular Weight]
450.34 |
| Hazard Information | Back Directory | [Uses]
Adenosine 3′,5′-cyclic monophosphate tris salt has been used as a medium supplement for human endometrial stromal cells (hESCs) culture and induced neural stem cells (iNSCs). It has been used in the spectroscopic characterization of pink flamindo, a red cAMP indicator. | [General Description]
Adenosine 3′,5′-cyclic monophosphate (cAMP) is synthesized from ATP in the presence of Adenylate cyclase enzyme. cAMP is majorly used as a marker in immunochemical detection assays. Intracellular levels of cAMP control immune and inflammatory functions. Bacterial infection triggers intracellular cAMP production. Elevated levels of cAMP modulates mitogen-activated protein kinase (MAPK) in cancer. An altered cAMP level is implicated in pathogenesis of cataract and cardiovascular disease. A decrease in cAMP levels triggers impaired insulin secretion in diabetes. | [Biochem/physiol Actions]
Naturally-occurring activator of cyclic-AMP-dependent protein kinase (PKA). cAMP is an important second messenger that is linked in many systems to neurotransmitter- or hormone-induced receptor stimulation. The cAMP/PKA signaling pathway has been shown to inhibit cell proliferation, induce differentiation and lead to apoptosis. |
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