| Identification | Back Directory | [Name]
Nemadectin | [CAS]
102130-84-7 | [Synonyms]
AC-088
Nemadectin
LL-F-28249α
LL-F28249 alpha
S541A, LL-F28249 alpha
(6R,23S,25S)-5-O-Demethyl-28-deoxy-25-[(E)-1,3-dimethyl-1-butenyl]-6,28-epoxy-23-hydroxymilbemycin B
Milbemycin B,5-O-demethyl-28-deoxy-25-[(1E)-1,3-dimethyl-1-buten-1-yl]-6,28-epoxy-23-hydroxy-,(6R,23S)- | [Molecular Formula]
C36H52O8 | [MOL File]
102130-84-7.mol | [Molecular Weight]
612.79 |
| Chemical Properties | Back Directory | [alpha ]
D26 +133° (c = 0.3 in acetone) | [Boiling point ]
789.4±60.0 °C(Predicted) | [density ]
1.20±0.1 g/cm3(Predicted) | [pka]
12.46±0.70(Predicted) |
| Hazard Information | Back Directory | [Description]
The nemadectins are fermentation products of Streptomyces
cyaneogriseus noncyanogenus. Structurally, the
nemadectins lack a disaccharide group at C-13 but differ
from the milbemycins proper because they contain a
trisubstituted double bond at C-26 in their side chains. | [Uses]
Nemadectin is the dominant member of a class of milbemycins bearing unsaturated longer chain groups at the 25-position. Nemadectin shows pronounced nematocidal and insecticidal activity. Nemadectin is the starting material for moxidectin, a commercial anthelmintic. |
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