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1027847-67-1

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1027847-67-1 Structure

1027847-67-1 Structure
IdentificationBack Directory
[Name]

AMG-009
[CAS]

1027847-67-1
[Synonyms]

AMG-009
AMG009,AMG 009
Benzeneacetic acid, 4-[4-[(butylamino)carbonyl]-2-[[(2,4-dichlorophenyl)sulfonyl]amino]phenoxy]-3-methoxy-
[Molecular Formula]

C26H26Cl2N2O7S
[MDL Number]

MFCD30532598
[MOL File]

1027847-67-1.mol
[Molecular Weight]

581.46
Chemical PropertiesBack Directory
[Melting point ]

148.6 °C
[density ]

1.403±0.06 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

DMSO (Slightly), Methanol (Slightly)
[form ]

Solid
[pka]

4.20±0.10(Predicted)
[color ]

Pale Brown
Hazard InformationBack Directory
[Uses]

4-[4-[(Butylamino)carbonyl]-2-[[(2,4-dichlorophenyl)sulfonyl]amino]phenoxy]-3-methoxy-benzeneacetic Acid is a dual??prostanoid D receptor??(DP) and??chemoattractant receptor-homologous molecule expressed on Th2 cells??(CRTH2) antagonist. DP and CRTH2 are involved in mediating allergic reactions (asthma, allergic rhinitis, and atopic dermatitis). Compounds that inhibit these receptors may hold potential for treating allergic diseases.
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