| Identification | Back Directory | [Name]
1-[1-(1-Methylcyclooctyl)-4-piperidinyl]-2-(3R)-3-piperidinyl-1H-benzimidazoletrihydrochloride | [CAS]
1028969-49-4 | [Synonyms]
MCOPPB
MCOPPB trihydrochloride
MCOPPB trihydrochloride hydrate
MCOPPB 3HCl,MCOPPB trihydrochloride
1-[1-(1-methylcyclooctyl)piperidin-4-yl]-2-[(3R)-piperidin-3-yl]benzimidazole
1-[1-(1-Methylcyclooctyl)-4-piperidinyl]-2-[(3R)-3-piperidinyl]-1H-benzimidazole
1H-Benzimidazole, 1-[1-(1-methylcyclooctyl)-4-piperidinyl]-2-(3R)-3-piperidinyl-
1-[1-(1-Methylcyclooctyl)-4-piperidinyl]-2-(3R)-3-piperidinyl-1H-benzimidazoletrihydrochloride
1-(1-(1-Methylcyclooctyl)piperidin-4-yl)-2-(piperidin-3-yl)-1H-Benzo[d]imidazole trihydrochlor
1-(1-(1-Methylcyclooctyl)piperidin-4-yl)-2-(piperidin-3-yl)-1H-Benzo[d]imidazole trihydrochloride
1-[1-(1-Methylcyclooctyl)-4-piperidinyl]-2-[(3R)-3-piperidinyl]-1H-benzimidazole trihydrochloride hydrate | [Molecular Formula]
C26H40N4 | [MDL Number]
MFCD11840549 | [MOL File]
1028969-49-4.mol | [Molecular Weight]
408.62 |
| Chemical Properties | Back Directory | [Melting point ]
>249°C (dec.) | [Boiling point ]
576.5±50.0 °C(Predicted) | [density ]
1.18 | [storage temp. ]
Store at -20°C | [solubility ]
H2O: ≥13mg/mL | [form ]
powder | [pka]
9.67±0.10(Predicted) | [color ]
white to tan |
| Hazard Information | Back Directory | [Uses]
A potent non-peptide nociceptin/orphanin FQ peptide (NOP)-receptor full agonist [or opioid-receptor-like-1 (ORL1) receptor agonist]. It is the most potent, non-peptide NOP full agonists in vitro and a potent anxiolytic in the mice. It inhibited signaling through the NOP receptor in the mouse brain, suggesting that it penetrated into the brain after it was orally administered. It did not affect locomotor activity or memory, nor did it contribute to ethanol-induced hypnosis. |
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