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1030021-40-9

1030021-40-9 Structure

1030021-40-9 Structure
IdentificationBack Directory
[Name]

CMP5
[CAS]

1030021-40-9
[Synonyms]

CMP5
CMP-5 hydrochloride
CMP-5 hydrochloride (PRMT5-IN-5)
[Molecular Formula]

C21H22ClN3
[MDL Number]

MFCD07168944
[MOL File]

1030021-40-9.mol
[Molecular Weight]

351.88
Hazard InformationBack Directory
[Description]

CMP5 is a potent and selective PRMT5 Inhibitor. CMP5 showed to occupy hPRMT5 catalytic site and block symmetrically dimethylated S2Me-H4R3 & S2Me-H3R8 with no effect on the asymmetric methylation of H4R3 in lymphoblastoid cell lines at 40 μM. CMP-5 shows promise as a novel therapeutic_x000D_ approach for B-cell lymphomas.
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