ChemicalBook--->CAS DataBase List--->10318-26-0

10318-26-0

10318-26-0 Structure

10318-26-0 Structure
IdentificationBack Directory
[Name]

DIBROMODULCITOL
[CAS]

10318-26-0
[Synonyms]

NSC104800
NSC-104800
NSC 104800
Dibromdulcit
Dibromdulcitol
DIBROMODULCITOL
1,6-Dibromodulcitol
1,6-Dibromodideoxydulcitol
1,6-dibromo-1,6-dideoxydulcitol
1,6-dibromo-1,6-dideoxy-galactito
1,6-dibromo-1,6-dideoxygalactitol
1,6-dibromo-1,6-dideoxy-d-galactitol
(2R,3S,4R,5S)-1,6-dibromohexane-2,3,4,5-tetrol
[Molecular Formula]

C6H12Br2O6
[MDL Number]

MFCD00062938
[MOL File]

10318-26-0.mol
[Molecular Weight]

339.964
Chemical PropertiesBack Directory
[Melting point ]

187-188° (dec)
[Boiling point ]

511.2±50.0 °C(Predicted)
[density ]

1.8987 (rough estimate)
[refractive index ]

1.4840 (estimate)
[pka]

12.61±0.20(Predicted)
[CAS DataBase Reference]

10318-26-0
[EPA Substance Registry System]

Mitolactol (10318-26-0)
Raw materials And Preparation ProductsBack Directory
[Raw materials]

D-Mannitol-->1,6-DIBROMO-1,6-DIDEOXY-D-MANNITOL
Hazard InformationBack Directory
[General Description]

White powder. Insoluble in water.
[Air & Water Reactions]

Insoluble in water.
[Reactivity Profile]

A halogenated alcohol. Flammable and/or toxic gases are generated by the combination of alcohols with alkali metals, nitrides, and strong reducing agents. They react with oxoacids and carboxylic acids to form esters plus water. Oxidizing agents convert them to aldehydes or ketones. Alcohols exhibit both weak acid and weak base behavior. They may initiate the polymerization of isocyanates and epoxides.
[Health Hazard]

ACUTE/CHRONIC HAZARDS: DIBROMODULCITOL is toxic when ingested.
[Fire Hazard]

Data is not available for DIBROMODULCITOL, but DIBROMODULCITOL is probably combustible.
[Uses]

1,6-Dibromodulcitol is an intermediate in the synthesis of Dulcitol Diepoxide (D720515). Dulcitol Diepoxide is a cytostatic drug. Dulcitol Diepoxide can be used for treatment of leukemia, lung cancer, multiple myeloma, and nasopharyngeal carcinoma.
[Definition]

ChEBI: Mitolactol is an alcohol and an organobromine compound.
Safety DataBack Directory
[Safety Profile]

Poison by ingestion. Moderately toxic by intraperitoneal route. Questionable carcinogen with experimental carcinogenic, neoplastigenic, and tumorigenic data. Human mutation data reported. An anti-cancer agent taken orally. When heated to decomposition it emits very toxic fumes of Br-.
[Toxicity]

LD50 in rats (mg/kg): 1400 orally; 470 i.p. (Kellner)
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