Identification | Back Directory | [Name]
Iloprost-d4 (Major) | [CAS]
1035094-10-0 | [Synonyms]
Iloprost-d4 (Major) (5E)-5-[(3aS,4R,5R,6aS)-Hexahydro-5-hydroxy-4-[(1E,3S)-3-hydroxy-4-methyl-1-octen-6-yn-1-yl]-2(1H)-pentalenylidene]pentanoic-2,2,3,3-d4 acid | [Molecular Formula]
C22H32O4 | [MOL File]
1035094-10-0.mol | [Molecular Weight]
360.49 |
Chemical Properties | Back Directory | [storage temp. ]
Amber Vial, -20°C Freezer, Under inert atmosphere | [solubility ]
Benzene (Slightly) | [form ]
Solid | [color ]
Colourless to Pale Yellow Oil | [Stability:]
Light Sensitive, Temperature Sensitive |
Hazard Information | Back Directory | [Uses]
A labelled synthetic analogue of Prostacyclin (PGI2) used to treat pulmonary arterial hypertension (PAH), scleroderma, Raynaud''s phenomenon and ischemia. It acts through elevation of cAMP by binding to the prostacyclin receptor (IP receptor). Iloprost inhibits the ADP, thrombin, and collagen-induced aggregation of human platelets with an ED50 of about 13 nM. In whole animals, iloprost acts as a vasodilator, hypotensive, antidiuretic, and prolongs bleeding time. |
|
Company Name: |
Energy Chemical
|
Tel: |
021-58432009 400-005-6266 |
Website: |
http://www.energy-chemical.com |
Company Name: |
Pharma Affiliates
|
Tel: |
172-5066494 |
Website: |
https://www.chemicalbook.com/ShowSupplierProductsList694812/0.htm |
Company Name: |
NE Scientific
|
Tel: |
+1 (617) 651-6662 |
Website: |
www.chemicalbook.com/ShowSupplierProductsList19253/0_EN.htm |
|