| Identification | Back Directory | [Name]
2,4-Thiazolidinedione, 5-[(4-hydroxyphenyl)methylene]- | [CAS]
103788-60-9 | [Synonyms]
5-(4-hydroxybenzylidene)-2,4-thiazolidinedione
(Z)-5-(4-hydroxybenzylidene)thiazolidine-2,4-dione
5-[(4-hydroxyphenyl)methylene]-2,4-Thiazolidinedione
2,4-Thiazolidinedione, 5-[(4-hydroxyphenyl)methylene]-
(Z)-5-(4-hydroxybenzylidene)thiazolidine-2,4-dione(WX180325) | [Molecular Formula]
C10H7NO3S | [MDL Number]
MFCD00640639 | [MOL File]
103788-60-9.mol | [Molecular Weight]
221.23 |
| Hazard Information | Back Directory | [Uses]
5-[(4-Hydroxyphenyl)methylene]-2,4-thiazolidinedione is a 5-Benzylidene-2,4-thiazolidenedione derivative designed as inhibitors of angiogenesis targeting VEGFR-2. Also, it is an intermediate used in the synthesis of MSDC 0602 (M755420), which is an analogue of?thiazolidinediones, exhibits low affinity for binding and activation of peroxisome proliferator-activated receptor γ (PPARγ). Thiazolidinediones are effective insulin-sensitizing drugs for treating various metabolic and inflammatory diseases. |
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