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104195-17-7

104195-17-7 Structure

104195-17-7 Structure
IdentificationBack Directory
[Name]

SDZ NVI-085
[CAS]

104195-17-7
[Synonyms]

SDZ NVI-085
naphtoxazine
[4aR,(-)]-3,4,4aβ,5,10,10aα-Hexahydro-6-methoxy-4-methyl-9-methylthio-2H-naphth[2,3-b]-1,4-oxazine
[Molecular Formula]

C15H21NO2S
[MDL Number]

MFCD00897700
[MOL File]

104195-17-7.mol
[Molecular Weight]

279.4
Hazard InformationBack Directory
[Description]

SDZ-NVI-085, also known as Naphtoxazine, is an α1 adrenergic receptor agonist potentially for the treatment of cognitive disorders and major depressive disorder. SDZ-NVI-085 behaves as a competitive antagonist of 5-hydroxytryptamine. SDZ-NVI-085 shifted 5-HT concentration-effect curves to the right, in a concentration-dependent manner, and Schild regression gave a pA2 estimate of 8.0.
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