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ChemicalBook--->CAS DataBase List--->104777-61-9

104777-61-9

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104777-61-9 Structure

104777-61-9 Structure
IdentificationBack Directory
[Name]

3alpha-Akeboic acid
[CAS]

104777-61-9
[Synonyms]

3alpha-Akeboic acid
3-Epiakebonoic acid
3alpha-Akebonoic acid
(3alpha)-3-Hydroxy-30-noroleana-12,20(29)-dien-28-oic acid
30-Noroleana-12,20(29)-dien-28-oic acid, 3-hydroxy-, (3α)-
[Molecular Formula]

C29H44O3
[MDL Number]

MFCD20260963
[MOL File]

104777-61-9.mol
[Molecular Weight]

440.658
Chemical PropertiesBack Directory
[solubility ]

Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
[form ]

Powder
Hazard InformationBack Directory
[Description]

3α-Akebonoic acid shows interesting in vitro growth inhibitory activity against human tumor A549 and HeLa cell lines, it also shows significant in vitro α-glucosidase inhibitory activity. 3α-Akebonoic acid can interfer with presenilin-1 (PS1)/ β-site APP-cleaving enzyme 1 (BACE1) interaction and reduces Aβ production, the chemical interference of PS1/BACE1 interaction is a promising strategy for Alzheimer’s disease therapeutics.
[target]

Beta Amyloid | BACE
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