| Identification | Back Directory | [Name]
Nevirapine-d4 | [CAS]
1051418-95-1 | [Synonyms]
Nevirapine-d4
B2Nevirapine-d4
Nevirapine methyl D4
Nevirapine-d4 (cyclopropyl-2,2,3,3-d4)
d4-11-cyclopropyl-4-methyl-5H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6(11H)-one | [Molecular Formula]
C15H14N4O | [MOL File]
1051418-95-1.mol | [Molecular Weight]
266.3 |
| Chemical Properties | Back Directory | [storage temp. ]
Store at -20°C | [solubility ]
DMF: 5 mg/ml,DMF:PBS (pH 7.2) (1:1): 0.5 mg/ml,DMSO: 2.5 mg/ml | [form ]
A solid | [color ]
White to off-white |
| Hazard Information | Back Directory | [Description]
Nevirapine-d4 is intended for use as an internal standard for the quantification of nevirapine by GC- or LC-MS. Nevirapine is a non-nucleoside reverse transcriptase inhibitor (NNRTI). It binds to HIV-1 reverse transcriptase and inhibits RNA plus-strand initiation (IC50 = 0.45 μM). Nevirapine prevents seroconversion and viremia in a chimpanzee model of HIV-1 infection. Formulations containing nevirapine have been used in combination therapy for the treatment of HIV-1 infection. | [Uses]
Nevirapine-d4 (cyclopropyl-2,2,3,3-d4) (CAS# 1051418-95-1) is a useful isotopically labeled research compound. This can be prepared to use as non-nucleoside reverse transcriptase inhibitors. | [storage]
Store at -20°C |
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